[HTML][HTML] The leukotriene receptor antagonist montelukast as a potential COVID-19 therapeutic

L Aigner, F Pietrantonio… - Frontiers in molecular …, 2020 - frontiersin.org
… might be potential candidates for COVID-19 therapeutics. This … leukotrienes in COVID-19,
and the rational for the use of the leukotriene receptor antagonist montelukast as a COVID-19

Possible therapeutic potential of cysteinyl leukotriene receptor antagonist montelukast in treatment of SARS-CoV-2-induced COVID-19

M Dey, RK Singh - Pharmacology, 2021 - karger.com
… occurrence of COVID-19 cases [18] and lung function deterioration [19] among the montelukast-…
patients were significantly reduced as compared to the nonmontelukast group [18, 19]. …

Role of leukotriene pathway and montelukast in pulmonary and extrapulmonary manifestations of Covid-19: The enigmatic entity

HM Al-Kuraishy, AI Al-Gareeb, YQ Almulaiky… - European journal of …, 2021 - Elsevier
… to elucidate the potential role of leukotrienes (LTs) in the … role of LT pathway receptor
antagonists and inhibitors in Covid-19 … ”, “leukotriene receptor antagonist OR leukotriene synthesis …

Effect of montelukast therapy on clinical course, pulmonary function, and mortality in patients with COVID19

B Kerget, F Kerget, M Aydın… - Journal of Medical …, 2022 - Wiley Online Library
… (cysLT) receptor antagonist with anti-inflammatory … leukotriene receptors and activate the
NF-κB pathway via the NF-κB transcription factor. Montelukast is a cysLT receptor 1 antagonist

[HTML][HTML] A novel strategy to mitigate the hyperinflammatory response to COVID-19 by targeting leukotrienes

CD Funk, A Ardakani - Frontiers in pharmacology, 2020 - frontiersin.org
… a 5-lipoxygenase inhibitor (zileuton) and an LTRA (montelukast). Montelukast has been in
… We suggest a treatment paradigm with two leukotriene modifiers zileuton CR/montelukast in …

[HTML][HTML] Levocetirizine and montelukast in the COVID-19 treatment paradigm

BC May, KH Gallivan - International Immunopharmacology, 2022 - Elsevier
… , and montelukast, a leukotriene receptor antagonist, exhibit … to treat the symptoms of
COVID-19. Clinical data to date with … many of the aspects of ‘Long COVID,’ thereby cost effectively …

Montelukast in hospitalized patients diagnosed with COVID-19

AR Khan, C Misdary, N Yegya-Raman, S Kim… - Journal of …, 2022 - Taylor & Francis
… of COVID-19, but few approaches have been proven efficacious. Because leukotriene receptor
antagonists, such as montelukast … with montelukast could be used to treat COVID-19. The …

[HTML][HTML] Montelukast drug activity and potential against severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2)

DC Copertino Jr, RRR Duarte, TR Powell… - Journal of Medical …, 2021 - ncbi.nlm.nih.gov
COVID19 is at least partially caused by mast cell activation, and leukotriene receptor antagonists
like montelukast … into the role of montelukast in SARS‐CoV‐2 prevention or COVID19

Montelukast as a potential treatment for COVID-19

MW McCarthy - Expert opinion on pharmacotherapy, 2023 - Taylor & Francis
… could also potentially serve as a treatment for COVID-19 [… to review the pleiotropic effects of
montelukast and to explore how … potential role for a selective leukotriene receptor antagonist. …

[HTML][HTML] Montelukast inhibits platelet activation induced by plasma from COVID-19 patients

M Camera, P Canzano, M Brambilla… - Frontiers in …, 2022 - frontiersin.org
Leukotriene receptor antagonists, such as montelukast, have … lavage of COVID-19 patients,
and montelukast, in addition to its … platelet activation characteristic of COVID-19 syndrome. In …