[PDF][PDF] Coronavirus-19 (SARS-CoV-2) induces acute severe lung inflammation via IL-1 causing cytokine storm in COVID-19: a promising inhibitory strategy

P Conti, A Caraffa, CE Gallenga, R Ross… - J Biol Regul Homeost …, 2020 - researchgate.net
… causative agent of coronavirus disease-19 (COVID-19), an … severe COVID-19 disease induced
by SARS-CoV-2 coronavirus… including lungs, and provoking cough, systemic inflammation

[PDF][PDF] Induction of pro-inflammatory cytokines (IL-1 and IL-6) and lung inflammation by Coronavirus-19 (COVI-19 or SARS-CoV-2): anti-inflammatory strategies

P Conti, G Ronconi, AL Caraffa… - J Biol Regul Homeost …, 2020 - researchgate.net
Coronavirus-19 (COVI-19) involves humans as well as animals and may cause serious damage
to the respiratory tract, including the lung: coronavirus disease (COVI-19)… When COVI-19

[HTML][HTML] The trinity of COVID-19: immunity, inflammation and intervention

MZ Tay, CM Poh, L Rénia, PA MacAry… - Nature Reviews …, 2020 - nature.com
… , which triggers a cytokine storm that mediates widespread lung inflammation. It was observed
that patients with severe COVID-19, requiring intensive care in hospitals, exhibited higher …

COVID-19: hemoglobin, iron, and hypoxia beyond inflammation. A narrative review

A Cavezzi, E Troiani, S Corrao - Clinics and practice, 2020 - mdpi.com
… conversely low in COVID-19 (HAPE-like) lung involvement, until critical respiratory insufficiency
occurs.Basically, clinical/instrumental features of lung disease in COVID-19 seem to shift …

[HTML][HTML] Lung-centric inflammation of COVID-19: Potential modulation by vitamin D

HMA Fakhoury, PR Kvietys, I Shakir, H Shams… - Nutrients, 2021 - mdpi.com
… CoV-2 in lung inflammation that can lead to the manifestations of severe COVID-19 such as
ARDS, … The potential impact of vitamin D at various stages of COVID-19 pathogenesis will be …

[PDF][PDF] How to reduce the likelihood of coronavirus-19 (CoV-19 or SARS-CoV-2) infection and lung inflammation mediated by IL-1

E Toniato, R Ross, SK Kritas - J Biol Regul Homeost Agents, 2020 - researchgate.net
… At present, there is no drug capable of treating CoV-19 flu, the only therapeutic … as
inflammation and pulmonary fibrosis, recognized as the first causes of death. One of the COVID-19

[PDF][PDF] Longitudinal profiling of respiratory and systemic immune responses reveals myeloid cell-driven lung inflammation in severe COVID-19

PA Szabo, P Dogra, JI Gray, SB Wells, TJ Connors… - Immunity, 2021 - cell.com
… driving COVID-19 lung pathology with therapeutic implications for targeting inflammation in
… Our results provide evidence for myeloid cell-driven lung inflammation in severe COVID-19

[HTML][HTML] Pathology of lung‐specific thrombosis and inflammation in COVID19

RR Khismatullin, AA Ponomareva… - Journal of Thrombosis …, 2021 - Elsevier
… Studying (ultra)structural features of the autopsy lung samples from patients with COVID19
link between inflammation and thrombosis. The major features in the lungs of COVID19

Between inflammation and thrombosis: endothelial cells in COVID-19

A Birnhuber, E Fliesser, G Gorkiewicz… - European …, 2021 - Eur Respiratory Soc
… We found that not only circulating levels of vWF but also its expression in the lung is strongly
elevated in severe COVID-19 patients. vWF is stored in and rapidly released from Weibel–…

[HTML][HTML] COVID-19 infection: the perspectives on immune responses

Y Shi, Y Wang, C Shao, J Huang, J Gan… - Cell Death & …, 2020 - nature.com
inflammation in the lungs that is largely mediated by pro-inflammatory macrophages and
granulocytes. Lung inflammation is … lung damage occurs, efforts should be made to suppress …