[HTML][HTML] MicroRNAs and cytokines as potential predictive biomarkers for COVID-19 disease progression

HA Mohamed, AE Abdelkafy, RMM Khairy… - Scientific reports, 2023 - nature.com
miRNAs in diagnosis of COVID-19 disease. ROC curve showed that miRNA-106a and
miRNA-20a downregulation in COVID-19 … P value = 0.0001*)) for miRNA-106a and (AUC = 0.86 ± …

Tackling the COVID-19 cytokine storm” with microRNA mimics directly targeting the 3'UTR of pro-inflammatory mRNAs

J Gasparello, A Finotti, R Gambari - Medical Hypotheses, 2021 - Elsevier
… approaches to counteract the COVID-19 induction of inflammatory response. … miRNA
mimics for inhibitory effects on the production of proteins characterizing the COVID-19cytokine

MicroRNAs based regulation of cytokine regulating immune expressed genes and their transcription factors in COVID-19

M Khokhar, S Tomo, P Purohit - Meta gene, 2022 - Elsevier
… Our analysis found miR-155-5p to be one of the ten identified miRNAs that possibly regulate
cytokine expression and triggers an inflammatory response in COVID-19. Further, miR-155-…

Cytokine storm in the pathophysiology of COVID-19: Possible functional disturbances of miRNAs

M Aslani, SS Mortazavi-Jahromi, A Mirshafiey - International …, 2021 - Elsevier
… the miRNAs-based therapeutic protocols. Accordingly, in this review article, we aim to discuss
the roles of key hsa-miRNAs in three main areas of severe/critical COVID-19 pathogenesis …

[HTML][HTML] … of circulating miRNAs and cytokines between COVID-19 and community-acquired pneumonia uncovers novel physiopathological mechanisms of COVID-19

P Martínez-Fleta, P Vera-Tomé… - Frontiers in …, 2022 - frontiersin.org
… plasma miRNAs and cytokines profiles between COVID-19 and … miRNAs between COVID-19
and CAP patients. Additionally, multivariate analysis displayed a combination of 4 miRNAs (…

Effect of miRNAs, Proinflammatory Cytokines and ACE2 in COVID-19 Pathophysiology

HO Singh, K Jakhar, V Nema, A Krishnaraj… - …, 2021 - ingentaconnect.com
… The pathogenesis of COVID-19 disease is not well understood. Hence we
comprehended the role of miRNAs, pro-inflammatory cytokines, and ACE2 genes in COVID-19

[HTML][HTML] The Effect of Host miRNAs on Prognosis in COVID-19: miRNA-155 May Promote Severity via Targeting Suppressor of Cytokine Signaling 1 (SOCS1) Gene

A Gedikbasi, G Adas, N Isiksacan, K Kart Yasar… - Genes, 2022 - mdpi.com
… This study investigated the relationship between the severity of COVID-19 disease and
alterations in the host’s miRNAs based on miRNA-mediated pathways and epigenetic regulation. …

[HTML][HTML] Cytokines and microRNAs in SARS-CoV-2: What do we know?

FZ Rarani, B Rashidi, MHJN Abadi, MR Hamblin… - … Therapy-Nucleic Acids, 2022 - cell.com
… , and whether they can be used in COVID-19 treatment. Moreover, we highlight … microRNAs
that are involved in these cytokines and their role in the cytokine storm caused by COVID-19

AntagomiRs: A novel therapeutic strategy for challenging COVID-19 cytokine storm

S Gangemi, A Tonacci - Cytokine & growth factor reviews, 2021 - Elsevier
… 1β, and IL-8, cytokines found to be involved in the … cytokine storm occurring in the COVID-19.
Another evidence in favour of the association between miRNAs and inflammatory cytokines

[HTML][HTML] The miRNA neuroinflammatory biomarkers in COVID-19 patients with different severity of illness

R Keikha, SM Hashemi-Shahri, A Jebali - Neurología, 2023 - Elsevier
… Of course, it is clear that this situation follows a cytokine storm. Unfortunately, we have to say
… We think that when immune cells are highly stimulated, cytokines and miRNAs can travel …