Myeloid cells in COVID-19 microenvironment

G Qin, S Liu, L Yang, W Yu, Y Zhang - Signal Transduction and …, 2021 - nature.com
… another myeloid cell subset is significant for the poor prognosis of severe COVID-19 patients…
trajectory of myeloid cells and critical transcription factors in COVID-19 patients provides a …

Dysregulation of lung myeloid cells in COVID-19

B Salomé, A Magen - Nature Reviews Immunology, 2020 - nature.com
… of COVID-19, but the functional state of T cells in these patients is not known. Based on the
retrospective study of 522 patients with COVID-19 … tion in T cell numbers inversely correlates …

Myeloid-derived suppressor cells in COVID-19: A review

YV Perfilyeva, YO Ostapchuk, R Tleulieva, A Kali… - Clinical …, 2022 - Elsevier
COVID-19 and discuss the complex role of these cells in the immunopathology of COVID-19
in patients with severe COVID-19, emphasizing an important role of myeloid cells in the …

COVID-19 and myeloid cells: complex interplay correlates with lung severity

FR D'Alessio, NM Heller - The Journal of clinical …, 2020 - Am Soc Clin Investig
… + conventional dendritic cells preferentially migrate from … COVID-19. Thus, this study
increases the knowledge of specific myeloid subsets involved in the pathogenesis of COVID-19

[PDF][PDF] Severe COVID-19 is marked by a dysregulated myeloid cell compartment

J Schulte-Schrepping, N Reusch, D Paclik, K Baßler… - Cell, 2020 - cell.com
… Severe COVID-19 was marked by occurrence of neutrophil … the myeloid cell compartment
associated with severe COVID-19. … dysregulated myeloid cell responses to severe COVID-19. …

Severe COVID-19 recovery is associated with timely acquisition of a myeloid cell immune-regulatory phenotype

AC Trombetta, GB Farias, AMC Gomes… - Frontiers in …, 2021 - frontiersin.org
… In order to investigate myeloid cell phenotype contributing to the recovery of patients with
severe COVID-19, we compared the data obtained at admission and at discharge from the …

Suppressive myeloid cells are a hallmark of severe COVID-19

…, Deutsche COVID-19 OMICS Initiative (DeCOI) - MedRxiv, 2020 - medrxiv.org
… CD123 + neutrophils were detected at late stages in severe COVID-19. Collectively, our
study links highly dysregulated myeloid cell responses to severe disease courses of COVID-19. …

A shift towards an immature myeloid profile in peripheral blood of critically Ill COVID-19 patients

E Vadillo, K Taniguchi-Ponciano… - Archives of Medical …, 2021 - Elsevier
… Therefore, our results suggest that immature circulating myeloid cells of severe COVID-19
patients are enriched in transcripts related to TLR signaling that resemble the CRBPβ-…

Expansion of myeloid-derived suppressor cells in patients with severe coronavirus disease (COVID-19)

C Agrati, A Sacchi, V Bordoni, E Cimini… - Cell Death & …, 2020 - nature.com
… two patients with severe COVID-19 disease from presentation … COVID-19 disease, was
obtained at admission and analyzed for T-cell activation profile, myeloid-derived suppressor cells

Myeloid-derived suppressor cells in COVID-19: the paradox of good

G Grassi, S Notari, S Gili, V Bordoni, R Casetti… - Frontiers in …, 2022 - frontiersin.org
COVID-19. We then showed a massive expansion of PMN-MDSCs in severe COVID-19 patients
with the capacity to inhibit T-cell … In the same paper, we followed COVID-19 patients after …