Dysregulation of lung myeloid cells in COVID-19

B Salomé, A Magen - Nature Reviews Immunology, 2020 - nature.com
… of COVID-19, but the functional state of T cells in these patients is not known. Based on the
retrospective study of 522 patients with COVID-19 … 14 patients with COVID-19 and 3 controls. …

Myeloid dysregulation and therapeutic intervention in COVID-19

R Gu, T Mao, Q Lu, TT Su, J Wang - Seminars in immunology, 2021 - Elsevier
myeloid cell dysregulation, leading to immunopathology and severe disease, and discuss
potential therapeutic strategies targeting myeloid cells as a new paradigm for COVID-19

[PDF][PDF] Severe COVID-19 is marked by a dysregulated myeloid cell compartment

J Schulte-Schrepping, N Reusch, D Paclik, K Baßler… - Cell, 2020 - cell.com
… Severe COVID-19 was marked by occurrence of neutrophil … the myeloid cell compartment
associated with severe COVID-19. … dysregulated myeloid cell responses to severe COVID-19. …

[HTML][HTML] Myeloid-derived suppressor cells as a potential biomarker and therapeutic target in COVID-19

M Rowlands, F Segal, D Hartl - Frontiers in immunology, 2021 - frontiersin.org
… cell compartment, with increased myeloid-… and myeloid cell dysregulation in COVID-19
infection and discuss the potential of MDSCs as biomarkers and therapeutic targets in COVID-19

[HTML][HTML] Myeloid cells in COVID-19 microenvironment

G Qin, S Liu, L Yang, W Yu, Y Zhang - Signal Transduction and …, 2021 - nature.com
… another myeloid cell subset is significant for the poor prognosis of severe COVID-19 patients…
trajectory of myeloid cells and critical transcription factors in COVID-19 patients provides a …

Immune dysregulation and system pathology in COVID-19

M Jamal, HI Bangash, M Habiba, Y Lei, T Xie, J Sun… - Virulence, 2021 - Taylor & Francis
… Extreme myeloid cell compartment changes during COVID-19 were also reported by a
multipronged approach characterized by an elevation in HLA-DR hi CD11c hi /HLA-DR hi CD83 …

Hallmarks of immune response in COVID-19: Exploring dysregulation and exhaustion

A Mazzoni, L Salvati, L Maggi, F Annunziato… - Seminars in …, 2021 - Elsevier
… The six hallmarks are dysregulated type I IFN activity, hyperinflammation, … , dysregulated
myeloid response, and heterogeneous adaptive immunity to SARS-CoV-2. Dysregulation and …

Myeloid-derived suppressor cells in COVID-19: A review

YV Perfilyeva, YO Ostapchuk, R Tleulieva, A Kali… - Clinical …, 2022 - Elsevier
… A dysregulated myeloid cell compartment is one of the most striking immunopathologic …
of myeloid cells with immunoregulatory activities in the periphery and airways of COVID-19

COVID-19 disease and immune dysregulation

E Davitt, C Davitt, MB Mazer, SS Areti… - Best Practice & …, 2022 - Elsevier
… levels of STAT3 phosphorylation in myeloid and lymphocytic cells [… was accompanied by
decreased myeloid cell activation in … pathway for the dysregulation observed in COVID-19 [18]. …

[HTML][HTML] COVID-19 and myeloid cells: complex interplay correlates with lung severity

FR D'Alessio, NM Heller - The Journal of clinical …, 2020 - Am Soc Clin Investig
… and dysregulated immune responses involving T and myeloid cells occur in COVID-19
In addition, the role of CD8+ T cells present in the lung of COVID-19 patients and relevant …