Nicotine and the nicotinic cholinergic system in COVID19

Y Tizabi, B Getachew, RL Copeland… - The FEBS …, 2020 - Wiley Online Library
… on the potential role of nicotine in COVID-19 pathology have recently been offered, we
believe that nicotine itself, through its interaction with the nicotinic cholinergic system, as well as …

[HTML][HTML] Nicotinic cholinergic system and COVID-19: In silico evaluation of nicotinic acetylcholine receptor agonists as potential therapeutic interventions

N Alexandris, G Lagoumintzis, CT Chasapis… - Toxicology reports, 2021 - Elsevier
… among hospitalized COVID-19 patients. These findings led to our hypothesis that the
Nicotinic Cholinergic System (NCS) plays a crucial role in the manifestation of COVID-19 and its …

COVID-19 and the nicotinic cholinergic system

K Farsalinos, A Angelopoulou… - European …, 2020 - Eur Respiratory Soc
… hospitalised COVID-19 patients… nicotinic cholinergic system and clinical manifestations of
the disease raise some important research questions, considering that nicotine is a cholinergic

[HTML][HTML] Nicotinic cholinergic system and COVID-19: in silico identification of an interaction between SARS-CoV-2 and nicotinic receptors with potential therapeutic …

K Farsalinos, E Eliopoulos, DD Leonidas… - International journal of …, 2020 - mdpi.com
… patients have shown a low prevalence of smoking among hospitalized COVID-19 … the
nicotinic cholinergic system (NCS) may be implicated in the pathophysiology of severe COVID-19, …

[HTML][HTML] Disorders of the cholinergic system in COVID-19 era—a review of the latest research

M Kopańska, M Batoryna, P Bartman… - International journal of …, 2022 - mdpi.com
… on the influence of COVID-19 on the cholinergic system is an … COVID-19 causes a
dysregulation of the cholinergic system, … -2 virus from binding to the nicotinic receptor. There is a …

[HTML][HTML] Cholinergic dysfunction in COVID-19: frantic search and hoping for the best

EH Nadwa, HM Al-Kuraishy, AI Al-Gareeb… - Naunyn-Schmiedeberg's …, 2023 - Springer
system (ANS). Therefore, this review aimed to elucidate the critical role of the cholinergic
system (… Nicotine and other nicotinic cholinergic agonists are FDA-approved drugs for several …

[HTML][HTML] Nicotine and SARS-CoV-2: COVID-19 may be a disease of the nicotinic cholinergic system

K Farsalinos, R Niaura, J Le Houezec… - Toxicology …, 2020 - ncbi.nlm.nih.gov
… This would explain the mild symptoms in COVID-19 patients with olfactory loss. In any
case, … of the nicotinic cholinergic system in COVID-19. A prominent feature of COVID-19 is …

COVID-19, a disease of the nicotinic cholinergic system? nicotine may be protective

K Farsalinos, R Niaura, K Poulas - Qeios [internet], 2020 - scholar.archive.org
… briefly the hypothesis that COVID-19 could be a disease of the nicotinic cholinergic system.
… , we make the hypothesis that COVID-19 could be a disease of the nicotinic cholinergic

[HTML][HTML] A nicotinic hypothesis for Covid-19 with preventive and therapeutic implications

JP Changeux, Z Amoura… - Comptes …, 2020 - comptes-rendus.academie-sciences …
… could be potentiated by the Covid-19 elicited nicotinic receptor dysregulation, leading to a
… The non-neuronal cholinergic system contributes to the regulation of cell functions such as …

Nicotinic cholinergic system and COVID-19: In silico identification of interactions between α7 nicotinic acetylcholine receptor and the cryptic epitopes of SARS-Co-V …

G Lagoumintzis, CT Chasapis, N Alexandris… - Food and Chemical …, 2021 - Elsevier
… This unusual correlation of smoking with a potential protective effect for COVID-19 was …
nicotinic cholinergic system (NCS) might be involved in the pathophysiology of severe COVID-19