… The data presented in this overview suggest that the NLRP3 inflammasome with its
downstream pathways is an attractive target for therapy of COVID-19 with (severe) pathology in …

… NLRP3 inflammasome in COVID-19, this review describes the possible pathways of NLRP3
inflammasome … , the role of the NLRP3 inflammasome in the pathogenesis of COVID-19 and …

… -containing 3 (NLRP3) inflammasome pathway and … COVID-19 and NLRP3 activation
and describe an important role in targeting this pathway for the treatment of severe COVID-19…

… NLRP3 inflammasome appears to be a potential drug target in the treatment of coronavirus
disease 2019 (COVID-19… This manuscript highlights the importance of NLRP3 inflammasome …

… However, ASC knockouts significantly decreased the levels of IL-1β (89), pointing to the
possibility that even if the NLRP3 inflammasome is blocked, other inflammasomes that require …

… In Covid-19, high neutrophil recruitment is correlated with disease severity; thereby
colchicine may reduce Covid-19 severity through inhibition of NLRP3 inflammasome, neutrophil …

… clinical symptoms in COVID-19, we aimed to suggest the possible role of NLRP3
inflammasome as a link between obesity and the increased risk for a severe COVID-19 outcome. …

… In this review, to delineate the interlink between NLRP3 inflammasome activation and
underlying conditions of COVID-19 severity, we focused on the mechanisms of NLRP3 mediated …

… COVID-19. We also summarize current efforts to target the NLRP3 inflammasome pathway in
COVID-19… and the therapeutic potential that inflammasome-targeted strategies may provide …

… The NLRP3 inflammasome is activated upon SARS-CoV-2 infection and … with COVID-19
severity. However, the processes by which the NLRP3 inflammasome is involved in COVID-19 …