Oral antiviral treatments for COVID-19: opportunities and challenges

L Rahmah, SO Abarikwu, AG Arero, M Essouma… - Pharmacological …, 2022 - Springer
… -based targets for oral antivirals development to treat COVID-19, highlight and compare the
main features, advantages, and limitations of the first-generation oral antiviral therapeutics (…

Molnupiravir, an oral antiviral treatment for COVID-19

W Fischer, JJ Eron Jr, W Holman, MS Cohen, L Fang… - MedRxiv, 2021 - medrxiv.org
… distributed oral antivirals are urgently needed to treat coronavirus disease-2019 (COVID-19), …
, and block transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)…

Antiviral treatment of COVID-19

S Yavuz, S Ünal - Turkish journal of medical sciences, 2020 - journals.tubitak.gov.tr
… In an open-label, controlled study of 80 patients with laboratory-confirmed COVID-19, 35
patients who received oral favipravir plus interferon (IFN)-α by aerosol inhalation were …

Antivirals and the potential benefits of orally inhaled drug administration in COVID-19 treatment

G Sahin, O Akbal-Dagistan, M Culha, A Erturk… - Journal of …, 2022 - Elsevier
… Therefore, a specific medication therapy for COVID-19 is … , among the current treatment
options, systemic antivirals are the … to summarize ongoing antiviral treatments in COVID-19, to …

Efficacy and safety of three new oral antiviral treatment (molnupiravir, fluvoxamine and Paxlovid) for COVID-19: a meta-analysis

W Wen, C Chen, J Tang, C Wang, M Zhou… - … of medicine, 2022 - Taylor & Francis
… In addition, we analysed the efficacy of three different antiviral drugs for COVID-19 patients,
and the OR was 0.22 (95% CI, 0.10–0.48) in the molnupiravir group, 0.45 (95% CI, 0.28–0.72…

Molnupiravir for oral treatment of Covid-19 in nonhospitalized patients

A Jayk Bernal, MM Gomes da Silva… - … Journal of Medicine, 2022 - Mass Medical Soc
Antiviral therapies that reduce the risk of Covid-19 progression are needed. Since trials have
shown the need for initiation of treatment as soon as possible after the onset of symptoms, 7…

Oral antiviral treatment for COVID-19: a comprehensive review on nirmatrelvir/ritonavir

K Akinosoglou, G Schinas, C Gogos - Viruses, 2022 - mdpi.com
COVID-19, the need to confine the pandemic and treat infected individuals on an outpatient
basis has led to the approval of oral antiviral … , delivered as an oral formulation, has shown …

[HTML][HTML] Role of favipiravir in the treatment of COVID-19

S Joshi, J Parkar, A Ansari, A Vora, D Talwar… - International Journal of …, 2021 - Elsevier
… of influenza and is being explored more for its role in the treatment of COVID-19. It is the first
oral antiviral drug approved for mild to moderate COVID-19. The already completed studies …

Comparative evaluation of authorized drugs for treating Covid19 patients

T Islam, M Hasan, MS Rahman… - Health Science …, 2022 - Wiley Online Library
Covid-19 patients with severe renal or hepatic impairment. Preliminary studies showed oral
antiviral drugs … four monoclonal antibodies for Covid-19 treatment. Studies suggest that these …

Molnupiravir and nirmatrelvir-ritonavir: oral coronavirus disease 2019 antiviral drugs

LD Saravolatz, S Depcinski… - Clinical Infectious …, 2023 - academic.oup.com
… This article reviews the 2 oral COVID-19 antiviral drugs including the mechanisms of action,
… the 2 oral COVID-19 antiviral drugs including the mechanisms of action, antiviral activity, …