Directly acting antivirals for COVID-19: where do we stand?

SL Teoh, YH Lim, NM Lai, SWH Lee - Frontiers in microbiology, 2020 - frontiersin.org
… known to be effective for COVID-19, multiple different antivirals have been examined based
… have represented an immediate and safe oral therapy for COVID-19. For most of the current …

Newer oral antivirals for COVID-19: Are they the real game changer?

S Kunal, P Sakthivel, N Malhotra… - Heart & Lung: The Journal …, 2022 - heartandlung.org
COVID-19 will become endemic, research should focus on identifying safe, affordable, and
globally accessible oral … surrounding the novel oral antiviral therapies in COVID-19 treatment. …

Molnupiravir: A new candidate for COVID19 treatment

F Pourkarim, S Pourtaghi‐Anvarian… - Pharmacology …, 2022 - Wiley Online Library
Antiviral medications are the candidate therapies for the management of COVID-19. … In this
study, EIDD-2801 was used as BID, 12 and 36 h after infection by oral gavage. Also, the effect …

[PDF][PDF] Plants as a prospective source of natural anti-viral compounds and oral vaccines against COVID-19 coronavirus

M Yonesi, A Rezazadeh - 2020 - researchgate.net
antiviral activity against COVID-19 disease, many other studies have assessed the antiviral
… against the previous generation of SARS related coronavirus, considerably SARS-Cov and …

The global COVID-19 treatment divide

AD Usher - The Lancet, 2022 - thelancet.com
… -changing COVID-19 drugs like Pfizer's oral antiviral Paxlovid (… 2 years after the emergence
of COVID-19, there is finally a … trial of its new oral antiviral treatment Paxlovid: hospitalisation …

Antiviral efficacy of molnupiravir for COVID-19 treatment

Y Bai, M Shen, L Zhang - Viruses, 2022 - mdpi.com
… the COVID-19 exposure to symptom onset [9]. There are 3 days on average from COVID-19
To evaluate the impact of antiviral therapy on the transmission dynamics of COVID-19, we …

[HTML][HTML] Antivirals for COVID-19: a critical review

A Frediansyah, R Tiwari, K Sharun, K Dhama… - … and global health, 2021 - Elsevier
… Although clinical trials to assess the efficacy of these antivirals … clinical uses of these antivirals
against COVID-19 pandemic. … by intra-venous route or orally. Ribavirin and sofosbuvir are …

Clinically approved antiviral drug in an orally administrable nanoparticle for COVID-19

B Surnar, MZ Kamran, AS Shah… - ACS pharmacology & …, 2020 - ACS Publications
COVID-19, a disease caused by a novel coronavirus strain called severe acute respiratory
syndrome coronavirus 2 … search for various therapeutics to combat COVID-19 infection with no …

Repurposed antiviral drugs for Covid-19—interim WHO solidarity trial results

WHO Solidarity Trial Consortium - New England journal of …, 2021 - Mass Medical Soc
… We randomly assigned inpatients with Covid-19 equally between one of the trial drug
regimens that was locally available and open control (up to five options, four active and the local …

Oral nirmatrelvir/ritonavir therapy for COVID-19: the dawn in the dark?

YP Hung, JC Lee, CW Chiu, CC Lee, PJ Tsai, IL Hsu… - Antibiotics, 2022 - mdpi.com
… However, administering antiviral therapy to people within three days of COVID-19 is a
clinical challenge, and the trial cohort was a part of a larger group who were treated within five …