Efficacy of antiviral therapies for COVID-19: a systematic review of randomized controlled trials

CTR Vegivinti, KW Evanson, H Lyons, I Akosman… - BMC Infectious …, 2022 - Springer
antivirals for COVID-19 treatment. Studies that were not randomized controlled trials or that
did not include treatment of COVID-19 with approved antiviralsantiviral efficacy for COVID-19

[HTML][HTML] Factors associated with viral rebound among COVID-19 patients receiving oral antivirals

PY Chen, JT Wang, SY Chang, CC Hung… - Journal of the Formosan …, 2023 - Elsevier
… In this study, we included only patients who completed oral antiviral treatments for their first
episodes of COVID-19, with at least three nasopharyngeal specimens sequentially collected …

[HTML][HTML] Characteristics and outcomes of patients with COVID-19 at high risk of disease progression receiving sotrovimab, oral antivirals or no treatment in England: a …

V Patel, MJ Yarwood, B Levick… - Current Medical …, 2024 - Taylor & Francis
… in high-risk COVID-19 patientsCitation 15 . The oral antiviral nirmatrelvir/ritonavir inhibits
the … the risk of progression to severe COVID-19 compared with placebo among symptomatic …

[HTML][HTML] An overview of the safety, clinical application and antiviral research of the COVID-19 therapeutics

D Wang, Z Li, Y Liu - Journal of infection and public health, 2020 - Elsevier
antivirals are currently available for COVID-19 caused by severe acute respiratory syndrome
coronavirus 2 (… Oral LL-37 antiviral peptide (CAS001) was another promising candidate and …

[HTML][HTML] Antiviral therapy in management of COVID-19: a systematic review on current evidence

M Yousefifard, A Zali, KM Ali… - Archives of academic …, 2020 - ncbi.nlm.nih.gov
… patients Lopinavir/Ritonavir 99 400 mg/100 mg twice daily Oral 14 Yes Lopinavir–ritonavir
administration is not superior to standard care in management of adult patients with severe …

Antiviral therapy of COVID-19

G Gudima, I Kofiadi, I Shilovskiy, D Kudlay… - International Journal of …, 2023 - mdpi.com
… treatment of COVID-19. In addition, here we describe innovative drugs whose antiviral effect
… Analysis of laboratory and clinical data suggests that current antivirals successfully combat …

Discovery of S-217622, a noncovalent oral SARS-CoV-2 3CL protease inhibitor clinical candidate for treating COVID-19

Y Unoh, S Uehara, K Nakahara, H Nobori… - Journal of medicinal …, 2022 - ACS Publications
… of COVID-19 vaccines, effective oral antiviral drugs are urgently needed. Here, we describe
the discovery of S-217622, the first oral … S-217622 exhibited antiviral activity in vitro against …

Covid-19: Pfizer's paxlovid is 89% effective in patients at risk of serious illness, company reports

E Mahase - 2021 - bmj.com
oral antiviral drug paxlovid significantly reduces hospital admissions and deaths among
people with covid-19 … three days of covid-19 symptoms starting, the risk of covid related hospital …

[HTML][HTML] Efficacy and safety of oral antivirals in individuals aged 80 years or older with mild-to-moderate COVID-19: preliminary report from an Italian Prescriber Center

G Bruno, S Perelli, M Giotta, N Bartolomeo… - Le Infezioni in …, 2022 - ncbi.nlm.nih.gov
… confirmed COVID-19 and mild-to-moderate illness who received an oral antiviral prescription
… The aim was to assess safety and effectiveness of oral antivirals in individuals ≥80 years …

Favipiravir: A new and emerging antiviral option in COVID-19

U Agrawal, R Raju, ZF Udwadia - Medical Journal Armed Forces India, 2020 - Elsevier
coronavirus. One of the drugs which has recently garnered much attention, especially in India,
is an anti-viral … the present pandemic to elucidate its role in the management of COVID-19. …