Role of monocytes/macrophages in Covid-19 pathogenesis: implications for therapy

J Gómez-Rial, I Rivero-Calle, A Salas… - Infection and Drug …, 2020 - Taylor & Francis
… /macrophages in previous coronavirus outbreaks and the emerging knowledge on their
role in COVID-19 pathogenesis… monocyte-macrophage, such as granulocyte macrophage-colony …

[HTML][HTML] Pathological inflammation in patients with COVID-19: a key role for monocytes and macrophages

M Merad, JC Martin - Nature reviews immunology, 2020 - nature.com
… BALF 23 from patients with severe COVID-19, and notably both … of macrophages has been
described in patients with COVID-19 … that the pathogenicity of infiltrating macrophages could …

Monocytes and macrophages in COVID-19: Friends and foes

S Meidaninikjeh, N Sabouni, HZ Marzouni, S Bengar… - Life sciences, 2021 - Elsevier
… role of macrophages and monocytes during the infection of SARS-CoV-2 in COVID-19 cases
… enhances the pathogenesis of COVID-19 and leads to an increase in mortality rates [9,47]. …

[HTML][HTML] Monocytes and Macrophages in COVID-19

R Knoll, JL Schultze, J Schulte-Schrepping - Frontiers in immunology, 2021 - frontiersin.org
… the immune response to an emerging pathogen during the COVID-19 pandemic. The first
transcriptomic immune atlas of circulating peripheral blood mononuclear cells (PBMC) from 10 …

[HTML][HTML] Alveolar macrophage dysfunction and cytokine storm in the pathogenesis of two severe COVID-19 patients

C Wang, J Xie, L Zhao, X Fei, H Zhang, Y Tan, X Nie… - …, 2020 - thelancet.com
… a direct viral entry into the monocytes/macrophages and highlighted the role of the aberrantly
activated macrophages as host cells of SARS-CoV-2 in COVID-19 disease mechanism. …

[HTML][HTML] Overview of the pathogenesis of COVID19

C Li, Q He, H Qian, J Liu - … and Therapeutic Medicine, 2021 - spandidos-publications.com
… , suggesting that PAMP-PRR signaling in macrophages may … In summary, the pathogenic
mechanisms of COVID-19 as a … to understand the pathogenic mechanisms of COVID-19. The …

Contribution of monocytes and macrophages to the local tissue inflammation and cytokine storm in COVID-19: Lessons from SARS and MERS, and potential …

A Jafarzadeh, P Chauhan, B Saha, S Jafarzadeh… - Life sciences, 2020 - Elsevier
… in the pathogenesis of COVID-19-, SARS- and MERS. Monocytes and macrophages may be
… can effectively suppress the anti-viral IFN response in monocytes and macrophages. Since …

HIF‐1, the Warburg Effect, and Macrophage/Microglia Polarization Potential Role in COVID19 Pathogenesis

E Ferraro, M Germanò, R Mollace… - Oxidative Medicine …, 2021 - Wiley Online Library
… clinical knowledge about coronavirus disease 2019 (COVID-19), knowledge … pathogenesis
of the maladaptive immune reaction against severe acute respiratory syndrome coronavirus-…

[HTML][HTML] Aveolar macrophage activation and cytokine storm in the pathogenesis of severe COVID-19

C Wang, J Xie, L Zhao, X Fei, H Zhang, Y Tan, L Zhou… - 2020 - europepmc.org
… , epithelium injuries, infiltration of macrophages and fibrosis in the … macrophages were
characteristic abnormalities. These findings shed new insights into the pathogenesis of COVID-19

Innate immunological pathways in COVID-19 pathogenesis

SR Paludan, TH Mogensen - Science immunology, 2022 - science.org
… similarities and differences between lung macrophages in COVID-19 and these diseases. …
progress in our understanding of COVID-19 pathogenesis and disease manifestations. …