The pro-inflammatory cytokines in COVID-19 pathogenesis: What goes wrong?

D Darif, I Hammi, A Kihel, IEI Saik, F Guessous… - Microbial …, 2021 - Elsevier
… , through either the pro-inflammatory cytokines or the activation of the … in COVID-19. Here,
we review the current understanding of pro-inflammatory cytokines associated with COVID-19

Cytokine storm and COVID-19: a chronicle of pro-inflammatory cytokines

A Fara, Z Mitrev, RA Rosalia, BM Assas - Open biology, 2020 - royalsocietypublishing.org
… The term ‘cytokine storm syndrome’ is perhaps one of the critical … COVID-19 disease severity.
In this review, we highlight prominent cytokine families and their potential role in COVID-19, …

[PDF][PDF] Induction of pro-inflammatory cytokines (IL-1 and IL-6) and lung inflammation by Coronavirus-19 (COVI-19 or SARS-CoV-2): anti-inflammatory strategies

P Conti, G Ronconi, AL Caraffa… - J Biol Regul Homeost …, 2020 - researchgate.net
… When COVI-19 infect the upper and lower respiratory tract it can cause mild or highly acute
… of pro-inflammatory cytokines, including interleukin (IL)-1β and IL-6. The binding of COVI-19

Cytokine release syndrome: inhibition of pro-inflammatory cytokines as a solution for reducing COVID-19 mortality

N Moradian, M Gouravani, MA Salehi, A Heidari… - European cytokine …, 2020 - Springer
… between these cytokines and severe or critical cases of COVID-19, we could hypothesize
that anti-IL-6 and anti-TNF antibodies could be effective for reducing COVID-19 mortality. In the …

[HTML][HTML] Characterisation of the pro-inflammatory cytokine signature in severe COVID-19

HC Hawerkamp, AH Dyer, ND Patil… - Frontiers in …, 2023 - frontiersin.org
… Whilst initial reports of CSS in severe/critical COVID-19 were debated, many subsequent
studies reframed the levels of circulating pro-inflammatory cytokines as a moderate cytokine

[HTML][HTML] Elevated interleukin-10 levels in COVID-19: potentiation of pro-inflammatory responses or impaired anti-inflammatory action?

H Islam, TC Chamberlain, AL Mui, JP Little - Frontiers in Immunology, 2021 - frontiersin.org
… of the coronavirus disease 2019 (COVID-19; caused by the SARS-CoV-2 virus) is the
overproduction of pro-inflammatory cytokines arising from excessive immune cell activation (ie, …

Serum profiles of pro-inflammatory and anti-inflammatory cytokines in non-hospitalized patients with mild/moderate COVID-19 infection.

AY Majeed, NES Zulkafli, AH Ad'hiah - Immunology Letters, 2023 - Elsevier
pro-inflammatory cytokines, anti-inflammatory cytokines have also been under the focus of
research in COVID-19cytokines that have shown dysregulated levels in COVID-19 patients …

[HTML][HTML] … cytokines in COVID-19 patients: A review on molecular mechanisms, immune functions, immunopathology and immunomodulatory drugs to counter cytokine …

AA Rabaan, SH Al-Ahmed, J Muhammad, A Khan… - Vaccines, 2021 - mdpi.com
COVID-19 syndrome is characterized by the uncontrolled and elevated release of pro-inflammatory
cytokines and … and pro-inflammatory cytokines. Thus, the clinical manifestations of …

[HTML][HTML] COVID-19: immunopathogenesis and Immunotherapeutics

L Yang, S Liu, J Liu, Z Zhang, X Wan… - Signal transduction and …, 2020 - nature.com
… by marked pro-inflammatory cytokine release in patients with severe COVID-19, leading to
… Therefore, mechanisms underlying immune abnormalities in patients with COVID-19 must …

Cytokines and COVID-19: friends or foes?

M Rokni, MR Hamblin, N Rezaei - Human vaccines & …, 2020 - Taylor & Francis
… of pro-inflammatory cytokines and chemokines, secreted by immune effector cells. …
cytokine storm also occurs in the recently emerged novel coronavirus disease (COVID-19). …