The pro-inflammatory cytokines in COVID-19 pathogenesis: What goes wrong?

D Darif, I Hammi, A Kihel, IEI Saik, F Guessous… - Microbial …, 2021 - Elsevier
… , through either the pro-inflammatory cytokines or the activation of the … in COVID-19. Here,
we review the current understanding of pro-inflammatory cytokines associated with COVID-19

[HTML][HTML] Elevated interleukin-10 levels in COVID-19: potentiation of pro-inflammatory responses or impaired anti-inflammatory action?

H Islam, TC Chamberlain, AL Mui, JP Little - Frontiers in Immunology, 2021 - frontiersin.org
… -classical pro-inflammatory effects of IL-10 as a driver of cytokine storms during COVID-19
elevated IL-10 levels in patients with severe COVID-19 (summarized in Figure 1). We also …

During sepsis and COVID-19, the pro-inflammatory and anti-inflammatory responses are concomitant

JM Cavaillon - Clinical Reviews in Allergy & Immunology, 2023 - Springer
… …), the host response is characterized by a pro-inflammatory reaction reflecting a systemic …
pro-inflammatory and anti-inflammatory response. Importantly, the intensity of both responses

Cytokine storm and COVID-19: a chronicle of pro-inflammatory cytokines

A Fara, Z Mitrev, RA Rosalia, BM Assas - Open biology, 2020 - royalsocietypublishing.org
… is plausibly linked to the hyperinflammatory response of the body … COVID-19 disease severity.
In this review, we highlight prominent cytokine families and their potential role in COVID-19

[HTML][HTML] A dynamic immune response shapes COVID-19 progression

EZ Ong, YFZ Chan, WY Leong, NMY Lee… - Cell host & …, 2020 - cell.com
… is to ask whether the inflammatory and immune responses to SARS-CoV-2 … COVID-19
patients and ten healthy volunteers. We found a highly dynamic expression of pro-inflammatory

[PDF][PDF] Induction of pro-inflammatory cytokines (IL-1 and IL-6) and lung inflammation by Coronavirus-19 (COVI-19 or SARS-CoV-2): anti-inflammatory strategies

P Conti, G Ronconi, AL Caraffa… - J Biol Regul Homeost …, 2020 - researchgate.net
… which induces other pro-inflammatory cytokines and inflammatory response, it is … -19 which
provokes pro-inflammatory IL-1 family member release. The suppression with IL-37 of CoV-19

[HTML][HTML] The systemic pro-inflammatory response: targeting the dangerous liaison between COVID-19 and cancer

GM Dettorre, M Patel, A Gennari, G Pentheroudakis… - ESMO open, 2021 - Elsevier
COVID-19 may uniquely benefit from strategies targeted at overcoming the unrestrained
pro-inflammatory response. … role of selective inhibition of pro-inflammatory interleukins, tyrosine …

Mechanism of inflammatory response in associated comorbidities in COVID-19

TMC de Lucena, AF da Silva Santos… - Diabetes & Metabolic …, 2020 - Elsevier
… As is being observed in COVID-19, MERS-CoV infection also … mechanisms of inflammatory
responses mediated by SARS-… a better immune response, reduce pro-inflammatory profile, …

[HTML][HTML] Characterisation of the pro-inflammatory cytokine signature in severe COVID-19

HC Hawerkamp, AH Dyer, ND Patil… - Frontiers in …, 2023 - frontiersin.org
… We assessed the immune response in acute COVID-19 by measuring 20 … response in
COVID-19, as well as more generally broadening our understanding of the immune response to …

[HTML][HTML] COVID-19: immunopathogenesis and Immunotherapeutics

L Yang, S Liu, J Liu, Z Zhang, X Wan… - Signal transduction and …, 2020 - nature.com
… antiviral immune responses, but can also cause uncontrolled inflammatory responses
characterized by marked pro-inflammatory cytokine release in patients with severe COVID-19, …