The pro-inflammatory cytokines in COVID-19 pathogenesis: What goes wrong?

D Darif, I Hammi, A Kihel, IEI Saik, F Guessous… - Microbial …, 2021 - Elsevier
… , through either the pro-inflammatory cytokines or the activation of the … in COVID-19. Here,
we review the current understanding of pro-inflammatory cytokines associated with COVID-19

Cytokine storm and COVID-19: a chronicle of pro-inflammatory cytokines

A Fara, Z Mitrev, RA Rosalia, BM Assas - Open biology, 2020 - royalsocietypublishing.org
… The term ‘cytokine storm syndrome’ is perhaps one of the critical … COVID-19 disease severity.
In this review, we highlight prominent cytokine families and their potential role in COVID-19, …

[HTML][HTML] COVID-19: immunopathogenesis and Immunotherapeutics

L Yang, S Liu, J Liu, Z Zhang, X Wan… - Signal transduction and …, 2020 - nature.com
… by marked pro-inflammatory cytokine release in patients with severe COVID-19, leading to
… Therefore, mechanisms underlying immune abnormalities in patients with COVID-19 must …

[HTML][HTML] The COVID-19 cytokine storm; what we know so far

D Ragab, H Salah Eldin, M Taeimah… - Frontiers in …, 2020 - frontiersin.org
COVID-19 poses an increasing threat to humans with a fatality rate of 6.4 % so far (4). COVID-19
… of a large amount of pro-inflammatory cytokines in an event known as “cytokine storm.” …

Proinflammatory cytokines in the olfactory mucosa result in COVID-19 induced anosmia

A Torabi, E Mohammadbagheri… - ACS chemical …, 2020 - ACS Publications
… local proinflammatory cytokine levels in the olfactory epithelium in patients with COVID-19.
Biopsies of the olfactory epithelium were taken from patients with confirmed COVID-19 as …

Cytokines and COVID-19: friends or foes?

M Rokni, MR Hamblin, N Rezaei - Human vaccines & …, 2020 - Taylor & Francis
… of pro-inflammatory cytokines and chemokines, secreted by immune effector cells. …
cytokine storm also occurs in the recently emerged novel coronavirus disease (COVID-19). …

[PDF][PDF] Induction of pro-inflammatory cytokines (IL-1 and IL-6) and lung inflammation by Coronavirus-19 (COVI-19 or SARS-CoV-2): anti-inflammatory strategies

P Conti, G Ronconi, AL Caraffa… - J Biol Regul Homeost …, 2020 - researchgate.net
Coronavirus-19 (COVI-19) involves humans as well as animals and may cause serious damage
to the respiratory tract, including the lung: coronavirus disease (COVI-19)… When COVI-19

[HTML][HTML] Characterisation of the pro-inflammatory cytokine signature in severe COVID-19

HC Hawerkamp, AH Dyer, ND Patil… - Frontiers in …, 2023 - frontiersin.org
… Our findings confirm a defined cytokine signature in severe COVID-19 (with elevated IL-2,
IL-6… the role of IP-10, G-CSF and IL-33 in the cytokine milieu associated with severe COVID-19. …

Emerging aspects of cytokine storm in COVID-19: The role of proinflammatory cytokines and therapeutic prospects

R Dharra, AK Sharma, S Datta - Cytokine, 2023 - Elsevier
cytokines in COVID-19-associated CS. We will particularly emphasize the role of GM-CSF …
G-CSF cytokines and other emerging therapeutic strategies adopted to mitigate COVID-19. …

Cytokine release syndrome: inhibition of pro-inflammatory cytokines as a solution for reducing COVID-19 mortality

N Moradian, M Gouravani, MA Salehi, A Heidari… - European cytokine …, 2020 - Springer
… between these cytokines and severe or critical cases of COVID-19, we could hypothesize
that anti-IL-6 and anti-TNF antibodies could be effective for reducing COVID-19 mortality. In the …