Inflammation resolution: a dual-pronged approach to averting cytokine storms in COVID-19?

D Panigrahy, MM Gilligan, S Huang, A Gartung… - Cancer and metastasis …, 2020 - Springer
… Targeting individual pro-inflammatory cytokines may not be sufficient to prevent COVID-19
those induced by COVID-19, by broadly inhibiting pro-inflammatory cytokine production and …

Cytokine profile and disease severity in patients with COVID-19

A Ghazavi, A Ganji, N Keshavarzian, S Rabiemajd… - Cytokine, 2021 - Elsevier
Cytokine dysregulation is the proposed mechanism for Coronavirus disease 2019 (COVID-19).
The … to evaluate serum levels of proinflammatory cytokines in patients with COVID-19. …

[PDF][PDF] Coronavirus-19 (SARS-CoV-2) induces acute severe lung inflammation via IL-1 causing cytokine storm in COVID-19: a promising inhibitory strategy

P Conti, A Caraffa, CE Gallenga, R Ross… - J Biol Regul Homeost …, 2020 - researchgate.net
… Therapies based on the reduction of proinflammatory cytokines in COVID-19 and … have a
therapeutic effect on COVID-19 patients through the inhibition of pro-inflammatory cytokines. …

Proinflammatory cytokines driving cardiotoxicity in COVID-19

M Colzani, J Bargehr, F Mescia… - Cardiovascular …, 2024 - academic.oup.com
COVID-19 confirmed patients on human embryonic stem cell (hESC)-derived cardiomyocytes.
We demonstrate that serum from COVID-19 … in non-COVID-19 acute respiratory distress …

COVID-19 infection: an overview on cytokine storm and related interventions

S Montazersaheb, SM Hosseiniyan Khatibi, MS Hejazi… - Virology journal, 2022 - Springer
… Growing evidence is being documented on the possible role of the pro-inflammatory
cytokines in COVID-19 pathogenesis and related complications [5]. With such a reason in mind, …

Cytokine storm in COVID-19: pathogenesis and overview of anti-inflammatory agents used in treatment

M Soy, G Keser, P Atagündüz, F Tabak… - Clinical …, 2020 - Springer
… SARS and COVID-19 infections may cause MAS and cytokine storm. T lymphocytes are
hyperactivated, and there is an enormous amount of pro-inflammatory cytokines including IL-6 …

Should we stimulate or suppress immune responses in COVID-19? Cytokine and anti-cytokine interventions

Y Jamilloux, T Henry, A Belot, S Viel, M Fauter… - Autoimmunity …, 2020 - Elsevier
Cytokines are central to the pathophysiology of COVID-19; … context of the so-called cytokine
storm. Yet another characteristic … of other proinflammatory cytokines such as TNF-α and IL-6. …

Cytokine patterns in COVID-19 patients: Which cytokines predict mortality and which protect against?

M Basheer, E Saad, M Kananeh, L Asad… - Current Issues in …, 2022 - mdpi.com
… of proinflammatory cytokines. This research studies the correlation of the released cytokines
with mortality or lung injury in COVID-19 … correlation between proinflammatory cytokines and …

The signal pathways and treatment of cytokine storm in COVID-19

L Yang, X Xie, Z Tu, J Fu, D Xu, Y Zhou - Signal transduction and …, 2021 - nature.com
… This is accompanied by an overwhelming production of pro-inflammatory cytokines in the
context of COVID-19, which not only impairs viral clearance but also promotes paradoxical …

The possible pathophysiology mechanism of cytokine storm in elderly adults with COVID-19 infection: the contribution of “inflame-aging”

GH Meftahi, Z Jangravi, H Sahraei, Z Bahari - Inflammation Research, 2020 - Springer
… release, which is described as cytokine storm, is a pivotal pathophysiological … in elderly
COVID-19 patients [4]. Aging is related to increased levels of systemic pro-inflammatory cytokines