The role of cytokines and their antagonists in the treatment of COVID19 patients

Z Mohseni Afshar, M Barary… - Reviews in medical …, 2023 - Wiley Online Library
… Even though cytokines are vital regulators of body immunoinflammatory responses, their …
severe COVID-19 infections, caused by the excessive release of pro-inflammatory cytokines, …

Basic predictive risk factors for cytokine storms in COVID-19 patients

SG Shcherbak, AY Anisenkova, SV Mosenko… - Frontiers in …, 2021 - frontiersin.org
… Objective: A critical role in coronavirus disease 2019 (COVID-19… of proinflammatory cytokines,
known as “a cytokine storm” (CS), … for CS development in COVID-19 patients and integrate …

Inflammatory Markers and Cytokines in Moderate and Critical Cases of COVID-19.

SH Chang, D Minn, SW Kim, YK Kim - Clinical Laboratory, 2021 - search.ebscohost.com
… This study aimed to investigate the inflammatory markers and cytokines in COVID-19
in severe COVID-19 [8,12]. A variety of different proinflammatory cytokines and chemokines …

Activation of NF-κB and induction of proinflammatory cytokine expressions mediated by ORF7a protein of SARS-CoV-2

CM Su, L Wang, D Yoo - Scientific reports, 2021 - nature.com
proinflammatory cytokines are elevated in severe COVID-19proinflammatory cytokines,
which is correlated with COVID-… molecular basis of cytokine storms in COVID-19 patients. The …

An inflammatory cytokine signature predicts COVID-19 severity and survival

DM Del Valle, S Kim-Schulze, HH Huang… - Nature medicine, 2020 - nature.com
… damage in patients with COVID-19 (ref. ). IL-1 is also a highly active pro-inflammatory cytokine,
and … IL-8 is a potent pro-inflammatory cytokine playing a key role in the recruitment and …

Complement anaphylatoxins and inflammatory cytokines as prognostic markers for COVID-19 severity and in-hospital mortality

B Alosaimi, A Mubarak, ME Hamed… - Frontiers in …, 2021 - frontiersin.org
… Our results indicated that the overactivation of the complement system and higher levels
of pro-inflammatory cytokines/chemokines in critical COVID-19 patients were significantly …

[PDF][PDF] A dynamic immune response shapes COVID-19 progression

EZ Ong, YFZ Chan, WY Leong, NMY Lee… - Cell host & …, 2020 - cell.com
COVID-19 consists of a spectrum of clinical syndromes ranging from mild, … COVID-19, as
laboratory investigations have also found elevated plasma levels of proinflammatory cytokines

Interleukin-6 perpetrator of the COVID-19 cytokine storm

J Shekhawat, K Gauba, S Gupta, P Purohit… - Indian Journal of Clinical …, 2021 - Springer
COVID-19 related CS (20). CS is characterised by elevated serum levels of pro-inflammatory
cytokines … Elevated levels of these pro-inflammatory cytokines in severe patients might be …

Risk factors for severe and critically ill COVID19 patients: a review

Y Gao, M Ding, X Dong, J Zhang, A Kursat Azkur… - Allergy, 2021 - Wiley Online Library
COVID-19. Old age and male gender are associated with more severe illness of COVID-19. …
immune defense, and higher levels of proinflammatory cytokines. ACE2, which may offer …

[PDF][PDF] COVID-19 induced by SARS-CoV-2 causes Kawasaki-like disease in children: Role of pro-inflammatory and anti-inflammatory cytokines

R Ross, P Conti - J. Biol. Regul. Homeost. Agents, 2020 - researchgate.net
… in COVID-19, Kawasaki disease and its similar forms are mediated by pro-inflammatory
cytokines … This is the first time to our knowledge that pro-inflammatory cytokines are reported to …