… The primary outcome for the COVID-PREVENT, HERO-19, and CONVINCE trials is the …
outcome for the randomized, double-blind, placebo-controlled ACTIV-4b trial is a composite of …

… plasma within 3 days after Covid-19 diagnosis. On the basis of all … In February 2020, the first
imported case of Covid-19 was … in Covid-19, we planned and conducted the PlasmAr trial to …

… We conducted a randomized, placebo-controlled, double-blind phase 2/3 trial in patients 18
… laboratory-confirmed Covid-19 with symptom onset 10 or fewer days before randomization. …

… We designed a pragmatic, randomized trial. In addition to the randomized trial, we also
collected data from patients who had not been randomized either because the patient had a …

… Trial Design and Oversight We conducted a randomized, double-blind, placebo-controlled
trial to evaluate postexposure prophylaxis with hydroxychloroquine after exposure to Covid-19…

… coronavirus 2 (SARS-CoV-2) infection are still needed to prevent severe coronavirus disease
2019 (Covid-19) … less severe Covid-19 in patients who were already receiving metformin. …

… randomized trial involving asymptomatic contacts of patients with polymerase-chain-reaction
(PCR)–confirmed Covid-19 … was PCR-confirmed, symptomatic Covid-19 within 14 days. The …

… Coronavirus disease-2019 (COVID-19). In these cases pharmacological prophylaxis would
be a solution to reduce severe acute respiratory syndrome coronavirus-2 (… for COVID-19. …

… is the first randomized clinical trial investigating treatment of COVID-19 among outpatients
(… COVID-19 revealed no published outpatient randomized clinical trials). This builds on other …

… randomized clinical trial of convalescent plasma in COVID-19… 28 days or mortality among
all randomized patients, but does … , should stimulate more clinical trials to establish the optimal …