… Based on the hypothesis that the RAAS can contribute to the genesis of the COVID-19-related cytokinestorm, ACE inhibitors and sartans have been studied in patients with COVID-19, …
L Yang, X Xie, Z Tu, J Fu, D Xu, Y Zhou - Signal transduction and …, 2021 - nature.com
… for the deterioration of COVID-19. Particularly, … cytokines are produced during the crosstalk between epithelial cells and immune cells in COVID-19, which has linked the cytokinestorm (…
P Sinha, MA Matthay, CS Calfee - JAMA internal medicine, 2020 - jamanetwork.com
… “cytokinestorm” been so closely associated with COVID-19? … cytokinestorm was described as a feature and associated … in COVID-19 reported levels of some plasma cytokines elevated …
JS Kim, JY Lee, JW Yang, KH Lee, M Effenberger… - Theranostics, 2021 - ncbi.nlm.nih.gov
… cytokine removal to treat the cytokinestormassociated with … treatments for the cytokinestorm in severe COVID-19. Last, we … (TPE) to treat cytokinestorm in severe COVID-19. We believe …
F Coperchini, L Chiovato, G Ricci, L Croce… - Cytokine & Growth …, 2021 - Elsevier
… Future studies will rapidly accumulate in the next months and their results will hopefully provide more insights as to the complex physiopathology of COVID-19-relatedcytokinestorm. …
… infection is limited to patients having lethal complications related to cytokinestorm such as ARDS, acute cardiac injury, renal failure, and to those patients with higher serum levels of D-…
D Ragab, H Salah Eldin, M Taeimah… - Frontiers in …, 2020 - frontiersin.org
… of the cytokinestormassociated with COVID-19 (35). The US Food and Drug Administration (FDA) has approved Roche's Phase III clinical trial of the use of tocilizumab in hospitalized …
L Tang, Z Yin, Y Hu, H Mei - Frontiers in immunology, 2020 - frontiersin.org
… may be the key link of cytokinestorm in COVID-19 (45). Moreover, the activation of monocytes may suggest that the cytokinestorm in COVID-19 is closely related to the destruction of the …
N Vaninov - Nature Reviews Immunology, 2020 - nature.com
… in COVID-19 Acute respiratory distress syndrome (ARDS) and robust cytokinestorm are the hallmark of severe COVID-19 … as IL-6 inhibitors, to treat COVID-19- associated inflammation. …