Genetic mechanisms of critical illness in COVID-19

E Pairo-Castineira, S Clohisey, L Klaric, AD Bretherick… - Nature, 2021 - nature.com
… Our findings reveal that critical illness in COVID-19 is related to at least two biological
mechanisms: innate antiviral defences, which are known to be important early in disease (IFNAR2 …

The role of illness behavior in the COVID-19 pandemic

F Cosci, J Guidi - Psychotherapy and Psychosomatics, 2021 - karger.com
… revealed significant levels of COVID-19-related worry [2… COVID-19 cases was found, as
well as among groups with greater social vulnerabilities [3]. Further, distress related to COVID-19

Pre-existing traits associated with Covid-19 illness severity

JE Ebinger, N Achamallah, H Ji, BL Claggett, N Sun… - PloS one, 2020 - journals.plos.org
… In our healthcare system, greater Covid-19 illness severity is seen in patients who are older,
male, African American, obese, with diabetes, and with greater overall comorbidity burden. …

COVID-19 extrapulmonary illness–special gastrointestinal and hepatic considerations

A Perisetti, M Gajendran, R Mann, S Elhanafi, H Goyal - Disease-a-Month, 2020 - Elsevier
… features related to GI manifestations in COVID-19, … COVID-19 have altered flora and increased
cytokine release, studies showed that IBD patients are not at risk of COVID-19 and related

[PDF][PDF] Rapid progression to acute respiratory distress syndrome: Review of current understanding of critical illness from coronavirus disease 2019 (COVID-19) …

KJ Goh, MC Choong, EHT Cheong… - Ann Acad Med …, 2020 - annals.edu.sg
… critical illness or markers of disease recovery. Management of ARDS in COVID-19 patients
… In this review, we examine current understanding of critical illness from COVID-19 infection …

Mental and neurological disorders and risk of COVID-19 susceptibility, illness severity and mortality: a systematic review, meta-analysis and call for action

L Liu, SY Ni, W Yan, QD Lu, YM Zhao, YY Xu… - …, 2021 - thelancet.com
… A total of 149 studies (227,351,954 participants, 89,235,737 COVID-19 patients) were included
in this analysis, in which 27 reported morbidity (132,727,798), 56 reported illness severity …

Underlying medical conditions associated with severe COVID-19 illness among children

L Kompaniyets, NT Agathis, JM Nelson… - JAMA network …, 2021 - jamanetwork.com
… a risk factor for severe COVID-19 illness among US children. … as a risk factor for severe
COVID-19 illness could be partially … -2 infection or indirect pandemic-related causes (eg, delays in …

Association between mental illness and COVID-19 susceptibility and clinical outcomes in South Korea: a nationwide cohort study

SW Lee, JM Yang, SY Moon, IK Yoo, EK Ha… - The Lancet …, 2020 - thelancet.com
… between mental illness and the severity of COVID-19 clinical outcomes… illness and COVID-19.
Meanwhile, clinicians should record the history of mental illness in patients with COVID-19

Correlates of critical illness-related encephalopathy predominate postmortem COVID-19 neuropathology

N Deigendesch, L Sironi, M Kutza, S Wischnewski… - Acta …, 2020 - Springer
… , including olfactory bulb and medulla oblongata in COVID-19 as well as control brains (Suppl. …
in COVID-19 patients represents a histopathological correlate of a critical illness-related

Characterization of the inflammatory response to severe COVID-19 illness

OJ McElvaney, NL McEvoy, OF McElvaney… - American journal of …, 2020 - atsjournals.org
… of the cytokinemia associated with coronavirus disease (COVID-19) are incompletely
understood. Data on immunometabolic alterations in patients with severe illness are scarce. …