Role of Lopinavir/Ritonavir in the treatment of Covid-19: a review of current evidence, guideline recommendations, and perspectives

S Meini, A Pagotto, B Longo, I Vendramin… - Journal of clinical …, 2020 - mdpi.com
… of the current COVID-19 pandemic, and the lack of therapies of proven efficacy should in
no way legitimize a failure of the scientific method. The validity of a given therapy must be …

[PDF][PDF] A Trial of Lopinavir-Ritonavir in Covid-19.

P Dalerba, B Levin, JL Thompson - N Engl J Med, 2020 - iris.unict.it
… We therefore advocate that therapeutic guidelines retain lopinavir–ritonavir as a treatment
option against Covid-19, pending completion of the World Health Organization SOLIDARITY …

[HTML][HTML] Paxlovid (Nirmatrelvir/Ritonavir): A new approach to Covid-19 therapy?

SMR Hashemian, A Sheida, M Taghizadieh… - Biomedicine & …, 2023 - Elsevier
… is of the ability to inhibit SARS-CoV-2 protease, ritonavir alone … of ritonavir and lopinavir in
COVID-19 treatment, lopinavir … study of COVID-19, the combination of lopinavir-ritonavir and …

Oral nirmatrelvir/ritonavir therapy for COVID-19: the dawn in the dark?

YP Hung, JC Lee, CW Chiu, CC Lee, PJ Tsai, IL Hsu… - Antibiotics, 2022 - mdpi.com
… drug reactions of nirmatrelvir/ritonavir can be expected in COVID-19 patients, as have
been … of oral nirmatrelvir/ritonavir therapy may effectively decrease the risk of COVID-19-related …

Efficacy of lopinavirritonavir combination therapy for the treatment of hospitalized COVID-19 patients: A meta-analysis

J Deng, F Zhou, W Hou, K Heybati, S Ali, O Chang… - Future …, 2022 - Taylor & Francis
… , is more beneficial compared with standard of care or adjuvant therapies alone in regards
… patients with COVID-19. We also examined the safety of LPV/r therapy in COVID-19 patients, …

Effectiveness of remdesivir, lopinavir/ritonavir, and favipiravir for COVID-19 treatment: a systematic review

WF Qomara, DN Primanissa, SH Amalia… - … journal of general …, 2021 - Taylor & Francis
… A combination of favipiravir with other supportive therapy showed more favorable outcomes
for COVID-19 patients. Furthermore, the use of lopinavir/ritonavir in COVID-19 patients …

[PDF][PDF] Clinical efficacy of lopinavir/ritonavir in the treatment of Coronavirus disease 2019.

XT Ye, YL Luo, SC Xia, QF Sun, JG Ding… - European Review for …, 2020 - europeanreview.org
therapeutic scheme against COVID-19. The study aimed to investigate whether lopinavir/ritonavir
(… pneumonia-associated adjuvant drugs has a better therapeutic effect on COVID-19. …

A systematic review of lopinavir therapy for SARS coronavirus and MERS coronavirus—A possible reference for coronavirus disease‐19 treatment option

TT Yao, JD Qian, WY Zhu, Y Wang… - Journal of medical …, 2020 - Wiley Online Library
… This study shows the positive effects of LPV/r therapy. Two reviews, including a Chinese
review and communication showed that LPV may be drug treatment option for COVID-19. …

A trial of lopinavirritonavir in adults hospitalized with severe Covid-19

B Cao, Y Wang, D Wen, W Liu, J Wang… - New England journal …, 2020 - Mass Medical Soc
… Thus far, there are no specific therapeutic agents for coronavirus infections. After the
emergence of severe acute respiratory syndrome (SARS) in 2003, screening of approved drugs …

[HTML][HTML] Efficacy and safety of lopinavir-ritonavir in COVID-19: A systematic review of randomized controlled trials

TK Patel, PB Patel, M Barvaliya, MK Saurabh… - Journal of Infection and …, 2021 - Elsevier
… A systematic review of lopinavir-ritonavir therapy in patients of … for the use of lopinavir-ritonavir
in the treatment of COVID-19 is now … in COVID-19 patients treated with lopinavir-ritonavir