The pro-inflammatory cytokines in COVID-19 pathogenesis: What goes wrong?

D Darif, I Hammi, A Kihel, IEI Saik, F Guessous… - Microbial …, 2021 - Elsevier
… to gather the current knowledge about the role of pro-inflammatory cytokines, namely IL-1β,
IL-… probable causes and clinical outcomes of this phenomenon in severe cases of COVID-19. …

Cytokine storm and COVID-19: a chronicle of pro-inflammatory cytokines

A Fara, Z Mitrev, RA Rosalia, BM Assas - Open biology, 2020 - royalsocietypublishing.org
… The term ‘cytokine storm syndrome’ is perhaps one of the critical … COVID-19 disease severity.
In this review, we highlight prominent cytokine families and their potential role in COVID-19, …

[HTML][HTML] … cytokines in COVID-19 patients: A review on molecular mechanisms, immune functions, immunopathology and immunomodulatory drugs to counter cytokine …

AA Rabaan, SH Al-Ahmed, J Muhammad, A Khan… - Vaccines, 2021 - mdpi.com
COVID-19 syndrome is characterized by the uncontrolled and elevated release of pro-inflammatory
cytokines … on the pivotal roles played by various inflammatory markers in COVID-19-…

[HTML][HTML] COVID-19: immunopathogenesis and Immunotherapeutics

L Yang, S Liu, J Liu, Z Zhang, X Wan… - Signal transduction and …, 2020 - nature.com
… by marked pro-inflammatory cytokine release in patients with severe COVID-19, leading to
… controlled and respiratory function is improved in patients with severe COVID-19 and that all …

Emerging aspects of cytokine storm in COVID-19: The role of proinflammatory cytokines and therapeutic prospects

R Dharra, AK Sharma, S Datta - Cytokine, 2023 - Elsevier
… the role of various cytokines in COVID-19-associated CS. We will particularly emphasize the
role of GM-CSF and G-CSF cytokines … therapeutic strategies adopted to mitigate COVID-19. …

Proinflammatory cytokines in the olfactory mucosa result in COVID-19 induced anosmia

A Torabi, E Mohammadbagheri… - ACS chemical …, 2020 - ACS Publications
… ) Recently, researchers from the University of California, San Francisco have used
chemosensory function changes as pretest predictors for COVID-19 positivity, and they believe that …

Cytokine release syndrome: inhibition of pro-inflammatory cytokines as a solution for reducing COVID-19 mortality

N Moradian, M Gouravani, MA Salehi, A Heidari… - European cytokine …, 2020 - Springer
… In this paper, the significant role of pro-inflammatory cytokines, including IL-1, IL-6, and
TNF-alpha, and their mechanism of action in the CRS cascade is explained. Potential therapeutic …

Cytokines and COVID-19: friends or foes?

M Rokni, MR Hamblin, N Rezaei - Human vaccines & …, 2020 - Taylor & Francis
… Citation5 Proinflammatory cytokines produced by Th cells … α were higher in severe COVID-19
patients, compared to those … and cytokines could result in impaired lung function ( Figure 1 )…

[PDF][PDF] Induction of pro-inflammatory cytokines (IL-1 and IL-6) and lung inflammation by Coronavirus-19 (COVI-19 or SARS-CoV-2): anti-inflammatory strategies

P Conti, G Ronconi, AL Caraffa… - J Biol Regul Homeost …, 2020 - researchgate.net
Coronavirus-19 (COVI-19) involves humans as well as animals … tract, including the lung:
coronavirus disease (COVI-19). This … (TNF) and IL-1 are of considerable importance (2, 18-19) …

[HTML][HTML] The COVID-19 cytokine storm; what we know so far

D Ragab, H Salah Eldin, M Taeimah… - Frontiers in …, 2020 - frontiersin.org
COVID-19 infection is accompanied by an aggressive inflammatory response with the release
of a large amount of pro-inflammatory cytokines in an event known as “cytokinefunctions