A systematic review on the efficacy and safety of chloroquine for the treatment of COVID-19

A Cortegiani, G Ingoglia, M Ippolito, A Giarratano… - Journal of critical …, 2020 - Elsevier
… evidence regarding chloroquine for the treatment of COVID-19. … safety from long-time clinical
use for other indications to justify clinical research on chloroquine in patients with COVID-19

Update I. A systematic review on the efficacy and safety of chloroquine/hydroxychloroquine for COVID-19

A Cortegiani, M Ippolito, G Ingoglia, P Iozzo… - Journal of critical …, 2020 - Elsevier
… observational study Patients with SLE and COVID-19 (n = 80) HCQ or chloroquine (in use
prior to COVID-19 for other clinical reasons) (n = 51) No HCQ or chloroquine regimens (n = 29…

[HTML][HTML] Efficacy and safety of chloroquine and hydroxychloroquine for treatment of COVID-19 patients-a systematic review and meta-analysis of randomized …

P Eze, KN Mezue, CU Nduka, I Obianyo… - American Journal of …, 2021 - ncbi.nlm.nih.gov
… benefit for chloroquine or hydroxychloroquine in the treatment of COVID-19 are likely …
were recently reported to benefit a subset of patients with COVID-19 [50-52]. Additionally, some …

Safety considerations for chloroquine and hydroxychloroquine in the treatment of COVID-19

S Gevers, MSG Kwa, E Wijnans… - Clinical …, 2020 - clinicalmicrobiologyandinfection …
… available, the off-label use of CQ/HCQ should be reserved only for COVID-19 patients
treated in context of clinical trials in order to improve our knowledge on safety and efficacy. …

Efficacy and safety of chloroquine or hydroxychloroquine in moderate type of COVID-19: a prospective open-label randomized controlled study

L Chen, ZY Zhang, JG Fu, ZP Feng, SZ Zhang, QY Han… - Medrxiv, 2020 - medrxiv.org
… clinical utility of chloroquine and hydroxychloroquine in treating COVID-19. … chloroquine in
treating COVID-19. Hydroxychloroquine is a derivative of chloroquine with an improved safety

Preliminary evidence from a multicenter prospective observational study of the safety and efficacy of chloroquine for the treatment of COVID-19

M Huang, M Li, F Xiao, P Pang, J Liang… - National Science …, 2020 - academic.oup.com
… , this study provides evidence for safety and efficacy of chloroquine in COVID-19 and suggests
that chloroquine can be a cost-effective therapy for combating the COVID-19 pandemic. …

Chloroquine dosage regimens in patients with COVID-19: Safety risks and optimization using simulations

V Karalis, G Ismailos, E Karatza - Safety science, 2020 - Elsevier
COVID-19 pneumonia. However, several safety concerns have been raised from chloroquine
… a critical appraisal of the safety information regarding chloroquine treatment and to apply …

Chloroquine and hydroxychloroquine for the treatment of COVID-19: a systematic review and meta-analysis

A Elavarasi, M Prasad, T Seth, RK Sahoo… - Journal of general …, 2020 - Springer
… that CQ or HCQ does not improve clinical outcomes in COVID-19. Well-designed randomized
trials are required for assessing the efficacy and safety of HCQ and CQ for COVID-19. …

Breakthrough: Chloroquine phosphate has shown apparent efficacy in treatment of COVID-19 associated pneumonia in clinical studies

J Gao, Z Tian, X Yang - Bioscience trends, 2020 - jstage.jst.go.jp
chloroquine phosphate, an old drug for treatment of malaria, had demonstrated marked efficacy
and acceptable safety in treating COVID-19 … , chloroquine was found to block COVID-19

Assessment of chloroquine and hydroxychloroquine safety profiles: a systematic review and meta-analysis

L Ren, W Xu, JL Overton, S Yu… - Frontiers in …, 2020 - frontiersin.org
… antiviral and immunomodulatory options for the treatment of 2019 coronavirus disease (COVID-19).
To examine the safety profiles of these medications, we systematically evaluated the …