In a search for potential drug candidates for combating COVID-19: computational study revealed salvianolic acid B as a potential therapeutic targeting 3CLpro and …

AA Elmaaty, KM Darwish, M Khattab… - Journal of …, 2022 - Taylor & Francis
Full article: In a search for potential drug candidates for combating COVID-19: computational
study revealed salvianolic acid B as a potential therapeutic targeting 3CLpro and spike …

Three salvianolic acids inhibit 2019‐nCoV spike pseudovirus viropexis by binding to both its RBD and receptor ACE2

S Hu, J Wang, Y Zhang, H Bai, C Wang… - Journal of medical …, 2021 - Wiley Online Library
… common complications associated with COVID-19, China's National … COVID-19 patients.
However, the efficacy and mechanism of SAA, SAB, and SAC in the treatment of COVID-19

Salvianolic acid C potently inhibits SARS-CoV-2 infection by blocking the formation of six-helix bundle core of spike protein

C Yang, X Pan, X Xu, C Cheng, Y Huang, L Li… - Signal transduction and …, 2020 - nature.com
… The pandemic of COVID-19 caused by SARS-CoV-2 … We herein report that the hydrophilic
compound Salvianolic acid C (… of Sal-C for COVID-19 therapies or prophylaxis and provides …

Anti-SARS-CoV-2 activities of tanshinone IIA, carnosic acid, rosmarinic acid, salvianolic acid, baicalein, and glycyrrhetinic acid between computational and in vitro …

D Elebeedy, WF Elkhatib, A Kandeil, A Ghanem… - RSC …, 2021 - pubs.rsc.org
… especially for tanshinone IIA (1) to be rapidly applied in COVID-19 management either
alone or in combination with carnosic acid (2), rosmarinic acid (3), and/or salvianolic acid (4). …

Salvia miltiorrhiza Bunge as a Potential Natural Compound against COVID-19

SJL Petitjean, M Lecocq, C Lelong, R Denis, S Defrère… - Cells, 2022 - mdpi.com
… phenolic compounds (such as salvianolic acids) are the major active … COVID-19. The first
study performed a screening of CM known to be biologically active against SARS coronavirus

Salvianolic acid B and its magnesium salt inhibit SARS-CoV-2 infection of Vero-E6 cells by blocking spike protein-mediated membrane fusion

C Yang, C Cheng, J Wang, K Chen, J Zhan… - … Fang yi ke da xue xue …, 2021 - europepmc.org
… Iinhibitory effects of salvianolic acid B (Sal-B) on entry of SARS-CoV-2 into the target cells. A:
… 老药新用”用于治疗COVID-19提供了可能性,也为COVID-19的心血管并发症治疗提供新的依据. …

Salvianolic Acid A Protects against Lipopolysaccharide‐Induced Acute Lung Injury by Inhibiting Neutrophil NETosis

Q Liu, C Zhu, H Li, J Xie, Y Guo, P Li… - Oxidative Medicine …, 2022 - Wiley Online Library
… is widely used in the treatment of ARDS, sepsis ,and COVID-19, leading to a statistically
significant improvement in clinical outcomes [25, 26]. Salvianolic acid A (SAA) (Figure 1), one …

[PDF][PDF] Salvia miltiorrhiza Bunge as a Potential Natural Compound against COVID-19. Cells 2022, 11, 1311

SJL Petitjean, M Lecocq, C Lelong, R Denis, S Defrère… - 2022 - academia.edu
… phenolic compounds (such as salvianolic acids) are the major active … COVID-19. The first
study performed a screening of CM known to be biologically active against SARS coronavirus

Salvianolactone acid A isolated from Salvia miltiorrhiza ameliorates lipopolysaccharide-induced acute lung injury in mice by regulating PPAR-γ

Q Zhang, M Zeng, B Zhang, Y Ren, S Li, R Wang, Y Hu… - Phytomedicine, 2022 - Elsevier
… Currently, novel coronavirus disease 2019 (COVID-19) pneumonia is ravaging the globe
and causing severe respiratory distress syndrome. Therefore, there is a great demand for new …

In silico drug discovery of major metabolites from spices as SARS-CoV-2 main protease inhibitors

MAA Ibrahim, AHM Abdelrahman, TA Hussien… - Computers in Biology …, 2020 - Elsevier
… inhibitors of COVID-19. … salvianolic acid A included the biochemical signaling genes ACE,
MAPK14 and ESR1; and for curcumin, EGFR and TNF. This study establishes salvianolic acid