The signal pathways and treatment of cytokine storm in COVID-19

L Yang, X Xie, Z Tu, J Fu, D Xu, Y Zhou - Signal transduction and …, 2021 - nature.com
… We also discuss the induction, function, downstream signaling, and existing and potential …
related signal pathways. We believe that a comprehensive understanding of CS in COVID-19

[HTML][HTML] Molecular pathways involved in COVID-19 and potential pathway-based therapeutic targets

M Farahani, Z Niknam, LM Amirabad… - Biomedicine & …, 2022 - Elsevier
… Given the elicited signaling pathways, we introduced possible pathway-based therapeutic
… of several signaling pathways involved in the immunopathogenesis of COVID-19. We also …

Inflammatory pathways in COVID19: Mechanism and therapeutic interventions

Y Jiang, T Zhao, X Zhou, Y Xiang… - MedComm, 2022 - Wiley Online Library
signaling pathways. We believe that a comprehensive understanding of the regulatory pathways
of COVID-19 … strategies to effectively control inflammatory diseases, such as COVID-19. …

An aberrant STAT pathway is central to COVID-19

T Matsuyama, SP Kubli, SK Yoshinaga… - Cell Death & …, 2020 - nature.com
… JAK (Janus kinase)-STAT signaling pathways they activate. JAK family kinases (JAK1, JAK2…
signaling network (see below), could result in almost all of the clinical features of COVID-19. …

PI3K/AKT signaling pathway: a possible target for adjuvant therapy in COVID-19

MR Khezri - Human Cell, 2021 - Springer
… /AKT signaling pathway has been linked to the induction of lung tissue fibrosis, which has
been detected in patients with COVID-19 [5, 7]. Regarding the role of this pathway in inducing …

[HTML][HTML] COVID-19 signalome: Pathways for SARS-CoV-2 infection and impact on COVID-19 associated comorbidity

K Lundstrom, A Hromić-Jahjefendić, E Bilajac… - … Signalling, 2023 - Elsevier
signaling pathways for SARS-CoV-2 infection and understand the impact of … pathway-pathway
interactions. Moreover, we describe the impact of the COVID-19 signalome on COVID-19

Innate immunological pathways in COVID-19 pathogenesis

SR Paludan, TH Mogensen - Science immunology, 2022 - science.org
… Although we are now starting to understand some of the PRRs and signaling pathways in
COVID-19 pathogenesis, a number of new questions arise. These relate to all aspects of the …

COVID-19: immunohistochemical analysis of TGF-β signaling pathways in pulmonary fibrosis

CB Vaz de Paula, S Nagashima, V Liberalesso… - International journal of …, 2021 - mdpi.com
… is observed in COVID-19. These findings … signaling pathways and pulmonary fibrosis.
The study consisted of 24 paraffin lung samples from patients who died of COVID-19 (COVID-19

Unpuzzling COVID-19: tissue-related signaling pathways associated with SARS-CoV-2 infection and transmission

DS Battagello, G Dragunas, MO Klein… - Clinical …, 2020 - portlandpress.com
… -coronavirus members. To better understand the development and transmission of COVID-19,
unveiling the signaling pathways … of cellular interaction and signaling pathways, elicited by …

Inflammatory cytokine: IL-17A signaling pathway in patients present with COVID-19 and current treatment strategy

T Shibabaw - Journal of inflammation research, 2020 - Taylor & Francis
… responsible for the immunopathology of COVID-19 and acute respiratory distress syndrome.
… IL-17A signaling and the synergic inflammatory cytokine IL-6 to manage COVID-19 patients, …