[HTML][HTML] The intersection of COVID-19 and cancer: signaling pathways and treatment implications

Z Zong, Y Wei, J Ren, L Zhang, F Zhou - Molecular cancer, 2021 - Springer
… the pandemic but also expand the treatment for COVID-19. In this review, we highlight the …
COVID-19 and summarize the four major signaling pathways at the intersection of COVID-19

[HTML][HTML] NF-κB pathway as a potential target for treatment of critical stage COVID-19 patients

R Kircheis, E Haasbach, D Lueftenegger… - Frontiers in …, 2020 - frontiersin.org
… lethality in COVID-19. The present perspective places a central cellular pro-inflammatory
signal pathway, NF-κB, in the context of recently published data for COVID-19 and provides a …

[HTML][HTML] Immune response in COVID-19: addressing a pharmacological challenge by targeting pathways triggered by SARS-CoV-2

M Catanzaro, F Fagiani, M Racchi, E Corsini… - Signal transduction and …, 2020 - nature.com
… in innate and adaptive immune system in COVID-19 patients. In particular, the massive …
signaling pathways triggered by SARS-CoV-2 infection. The identification of signaling pathways

Targeting the PI3K/Akt/mTOR pathway: A therapeutic strategy in COVID-19 patients

R Abu-Eid, FJ Ward - Immunology letters, 2021 - Elsevier
… Furthermore, this signalling pathway is essential for SARS-cov-2 virus … COVID-19 patients
to improve patient outcome. Targeting different levels of the PI3K/Akt/mTOR signalling pathway

[HTML][HTML] Cellular and molecular pathways of COVID-19 and potential points of therapeutic intervention

JP Hussman - Frontiers in pharmacology, 2020 - frontiersin.org
… (eg, FcγRIIA) and downstream signaling pathways (eg, NF-κB … with observed clinical markers
in COVID-19, including high … emerge, the proposed pathway suggests multiple points of …

The potential involvement of JAK-STAT signaling pathway in the COVID-19 infection assisted by ACE2

J Luo, S Lu, M Yu, L Zhu, C Zhu, C Li, J Fang, X Zhu… - Gene, 2021 - Elsevier
… for the study of COVID-19 infection. In this study, we demonstrated the expression features
of ACE2 in coronavirus infection and identified associated pathways of COVID-19 using gene …

[HTML][HTML] Janus kinase signaling pathway and its role in COVID-19 inflammatory, vascular, and thrombotic manifestations

JD Ravid, O Leiva, VC Chitalia - Cells, 2022 - mdpi.com
… Manifestations of Coronavirus Disease-19 Coronavirus Disease-19 (COVID-19) is a
worldwide public health crisis caused by the severe acute respiratory syndrome coronavirus 2 (…

Prediction and analysis of microRNAs involved in COVID-19 inflammatory processes associated with the NF-kB and JAK/STAT signaling pathways

Z Amini-Farsani, M Yadollahi-Farsani, S Arab… - International …, 2021 - Elsevier
COVID-19 is the cause of a pandemic associated with substantial morbidity and mortality.
As yet, there is no available approved drug to eradicate the virus. In this review article, we …

The PI3K/Akt/mTOR pathway: a potential pharmacological target in COVID-19

MS Basile, E Cavalli, J McCubrey… - Drug discovery today, 2022 - Elsevier
… cell signaling pathway observed in patients with COVID-19 has … of specific inhibitors of this
pathway for the treatment of the … pathway in severe acute respiratory syndrome coronavirus 2 (…

JAK-STAT pathway inhibition and their implications in COVID-19 therapy

S Satarker, AA Tom, RA Shaji, A Alosious… - Postgraduate …, 2021 - Taylor & Francis
… The viral infection could also further promote inhibition of inflammatory signaling pathways
causing immunosuppression [Citation57]. Recently, Bouwman and colleagues reported that …