[PDF][PDF] Heightened innate immune responses in the respiratory tract of COVID-19 patients

Z Zhou, L Ren, L Zhang, J Zhong, Y Xiao, Z Jia, L Guo… - Cell host & …, 2020 - cell.com
… For pathway analysis, we applied the Ingenuity Pathway … some’’ and ‘‘Chemokine signaling
pathway’’—formed two most … highly responsive state against noxious stimuli in COVID-19

COVID-19 and oxidative stress

BV Chernyak, EN Popova, AS Prikhodko… - Biochemistry …, 2020 - Springer
… Both endothelial pro-inflammatory activation as well as RAGE expression are driven by the
transcription factor NF-κB implicating that this signaling pathway is targeted by mtROS. This …

[HTML][HTML] A hypothesized role for dysregulated bradykinin signaling in COVID19 respiratory complications

JA Roche, R Roche - The FASEB Journal, 2020 - ncbi.nlm.nih.gov
… that dysregulated BK signaling is involved in COVID19 respiratory complications for the …
on BK signaling pathways, might also be able to reduce the respiratory distress in COVID19. …

The potential of JAK/STAT pathway inhibition by ruxolitinib in the treatment of COVID-19

BG Bagca, CB Avci - Cytokine & growth factor reviews, 2020 - Elsevier
… / STAT signaling pathway, one of the critical cellular signaling pathways involved in the
inflammatory response. This review presents an overview of SARS-CoV-2 and the COVID-19

Differential co-expression network analysis reveals key hub-high traffic genes as potential therapeutic targets for COVID-19 pandemic

A Hasankhani, A Bahrami, N Sheybani, B Aria… - Frontiers in …, 2021 - frontiersin.org
… study, in addition to apoptosis, the p53 signaling pathway was highly enriched in PBMCs
of the COVID-19 group and may be associated with lymphopenia in COVID-19 patients (97). …

An Overview on the Common Laboratory Parameter Alterations and their Related Molecular Pathways in Screening for COVID-19 Patients.

M Saberiyan, A Safi, A Kamel… - Clinical …, 2020 - search.ebscohost.com
… to study signaling pathways as … pathway, which supports the possibility that COVID-19
independently infects liver tissue and results in liver damage [11]. The monitoring of COVID-19

Computationally predicted SARS-COV-2 encoded microRNAs target NFKB, JAK/STAT and TGFB signaling pathways

MN Aydemir, HB Aydemir, EM Korkmaz, M Budak… - Gene Reports, 2021 - Elsevier
… a new type of beta coronavirus called severe acute respiratory disease coronavirus type
2 (… by the virus was named as coronavirus disease 19 (COVID19). Despite the information …

[HTML][HTML] … antiviral and coronavirus-host protein pathways inhibiting properties of herbs and natural compounds-Additional weapons in the fight against the COVID-19 …

AD Fuzimoto, C Isidoro - Journal of traditional and complementary medicine, 2020 - Elsevier
… Particularly, we paid attention to the mechanisms of action and/or signaling pathways involved
in the activity of such herbs and natural products that could support the ability to contrast …

[HTML][HTML] Tissue-specific pathway activities: A retrospective analysis in COVID-19 patients

N Pham, F Hu, CT Evelo, M Kutmon - Frontiers in immunology, 2022 - frontiersin.org
… in immune pathways between COVID-19 and non-COVID-19 … in COVID-19 such as type 1
interferon signalling pathway (… signalling pathway (WP366), IL-1 or IL-6 signalling pathway (…

mTOR inhibition in COVID19: A commentary and review of efficacy in RNA viruses

BS Karam, RS Morris, CT Bramante… - Journal of medical …, 2021 - Wiley Online Library
coronavirus 2 A recent pre-print identified the mTOR–PI3K–AKT pathway as a key signaling
pathway … -CoV-2 infected cells identified multiple pathways that exhibited in vitro modulation …