The common regulatory pathway of COVID-19 and multiple inflammatory diseases and the molecular mechanism of cepharanthine in the treatment of COVID-19

P Jiang, J Ye, M Jia, X Li, S Wei, N Li - Frontiers in pharmacology, 2022 - frontiersin.org
… The purpose of this work is to explore the common targets and signaling pathways among
COVID-19, RA, AS, and GA by means of network pharmacology (NP), and to infer the potential …

Extracellular vesicle associated miRNAs regulate signaling pathways involved in COVID-19 pneumonia and the progression to severe acute respiratory corona virus …

AS Meidert, S Hermann, F Brandes, B Kirchner… - Frontiers in …, 2021 - frontiersin.org
… from patients with COVID-19 pneumonia, COVID-19 ARDS, … With bioinformatically constructed
canonical pathways … differences in molecular signaling between COVID-19 and other …

Predicting COVID-19—comorbidity pathway crosstalk-based targets and drugs: towards personalized COVID-19 management

D Barh, AA Aljabali, MM Tambuwala, S Tiwari… - Biomedicines, 2021 - mdpi.com
… TLR signaling pathway was found to be shared by COVID-19signaling was recently reported
to be shared by COVID-19 … Fc epsilon RI inhibition signaling pathway could be a potential …

COVID19: immunopathology, pathophysiological mechanisms, and treatment options

LE van Eijk, M Binkhorst, AR Bourgonje… - The Journal of …, 2021 - Wiley Online Library
pathways and systems involved in the pathophysiology and immunopathogenesis of
COVID-19. … Inhibition of the TLR signalling pathway and thereby decreased cytokine production …

Drug-repurposing against COVID-19 by targeting a key signaling pathway: An in silico study

KK Oh, M Adnan, DH Cho - Medical Hypotheses, 2021 - Elsevier
signaling pathway in lung cells might dampen the COVID-19 … estrogen signaling pathway
with the development of COVID-19 … be promising alleviators for COVID-19 patients. This work …

Alzheimer's‐like signaling in brains of COVID19 patients

S Reiken, L Sittenfeld, H Dridi, Y Liu… - Alzheimer's & …, 2022 - Wiley Online Library
… inflammatory signaling and oxidative stress pathways resulting in … of COVID-19 patients,
we observed increased systemic oxidative stress and activation of the TGF-β signaling pathway

Ephrin (Eph) receptor and downstream signaling pathways: a promising potential targeted therapy for COVID19 and associated cancers and diseases

H Zalpoor, A Akbari, M Nabi-Afjadi - Human Cell, 2022 - Springer
… Currently, the coronavirus disease 2019 (COVID-19) … coronavirus-2 (SARS-CoV-2) is
responsible for COVID-19 and … receptor downstream signaling pathway for COVID-19-associated …

[HTML][HTML] Innate immune signaling and proteolytic pathways in the resolution or exacerbation of SARS-CoV-2 in Covid-19: key therapeutic targets?

JM Sallenave, L Guillot - Frontiers in immunology, 2020 - frontiersin.org
… An emphasis will be put on host cellular signaling pathways and proteases involved with
a … COVID-19 is a respiratory disease whose aetiologic agent is a novel beta coronavirus (CoV) …

Evaluation of the immunomodulatory effects of anti-COVID-19 TCM formulae by multiple virus-related pathways

L Qiao, W Huang, X Zhang, H Guo, D Wang… - Signal Transduction …, 2021 - nature.com
… NF-κB signaling pathway (Fig. 1e), which is a crucial pathway of cytokine storm in severe
COVID-19… In contrast, 26 formulae had a positive NES for virus-related pathways, indicating an …

Molecular mechanisms and signaling pathways involved in immunopathological events of COVID-19

AA Peyvandi, S Niknazar, F Zare Mehrjerdi… - Physiology and …, 2021 - ppj.phypha.ir
… Several pathways are associated with the COVID-19 pathogenesis and a significant … Here,
we focus on signaling pathways and molecular mechanisms that are involved in COVID-19