A new approach to the management of COVID-19. Antagonists of IL-6: Siltuximab

L Villaescusa, F Zaragozá, I Gayo-Abeleira… - Advances in …, 2022 - Springer
… patients with COVID-19 with severe … COVID-19. A literature search was conducted on the
clinical trials of siltuximab published to date as well as on the different IL-6 signalling pathways

[HTML][HTML] A novel coronavirus disease (COVID-19): A review of host cell signaling pathways

H Mohammadpour, A Ziai, M Sadr, M Rezaei… - Tanaffos, 2020 - ncbi.nlm.nih.gov
… We also discuss different host cell signaling pathways that can be considered in the … of
coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus

[HTML][HTML] Identifying potential drug targets and candidate drugs for COVID-19: biological networks and structural modeling approaches

G Selvaraj, S Kaliamurthi, GH Peslherbe… - F1000Research, 2021 - ncbi.nlm.nih.gov
Coronavirus and influenza are pathogens causing severe … complicated COVID-19 patients
than non-severe COVID-19 patients’ … transduction and cytokine immune signaling pathways. It …

COVID-19 revisiting inflammatory pathways of arthritis

G Schett, B Manger, D Simon, R Caporali - Nature Reviews …, 2020 - nature.com
… We first consider the musculoskeletal symptoms elicited by COVID-19. We then describe
how the mechanisms of alveolar inflammation in COVID-19 share similarities with those in …

Computational analysis illustrates the mechanism of Qingfei Paidu decoction in blocking the transition of COVID-19 patients from mild to severe stage

X Li, L Xiang, Y Lin, Q Tang, F Meng… - Current Gene …, 2022 - ingentaconnect.com
… , IL4, IFNG) in severe COVID-19 patients. By performing KEGG … pathways, namely TNF
signaling pathway, IL-17 signalingCOVID-19 by inhibiting the JAK-STAT signaling pathway [45, …

Review on the potential action mechanisms of Chinese medicines in treating Coronavirus Disease 2019 (COVID-19)

YF Huang, C Bai, F He, Y Xie, H Zhou - Pharmacological research, 2020 - Elsevier
… in the management of COVID-19 by multiple components acting on … signaling pathway,
IL-17 signaling pathway, and tuberculosis related pathway could be the key for treating COVID-19

Pathogenetic profiling of COVID-19 and SARS-like viruses

Z Nain, HK Rana, P Liò, SMS Islam… - Briefings in …, 2021 - academic.oup.com
COVID-19 disease. We also observed similarities in pathways that can lead to COVID-19
and … For example, we identified five pathways including chemokine signaling pathway NRF2 …

COVID-19 infection: an overview on cytokine storm and related interventions

S Montazersaheb, SM Hosseiniyan Khatibi, MS Hejazi… - Virology journal, 2022 - Springer
… has been paid to dampening signaling pathways of inflammatory cytokines aiming to reduce
inflammatory responses and mortality in patients suffering from COVID-19. According to the …

Quercetin for COVID-19 and DENGUE co-infection: a potential therapeutic strategy of targeting critical host signal pathways triggered by SARS-CoV-2 and DENV

W Zheng, H Wu, T Wang, S Zhan… - Briefings in …, 2021 - academic.oup.com
… Current studies have shown that quercetin is both resistant to COVID-19 and DENGUE;
this … quercetin as a potential molecular candidate against COVID-19 and DENGUE co-infection. …

The roles of signaling pathways in SARS-CoV-2 infection; lessons learned from SARS-CoV and MERS-CoV

N Hemmat, Z Asadzadeh, NK Ahangar… - Archives of …, 2021 - Springer
… these inflammatory cellular signaling pathways, and these … COVID-19. In this review, we
briefly summarize alterations of cellular signaling pathways that are associated with coronavirus