Sarilumab administration in COVID-19 patients: literature review and considerations

A Marino, A Munafò, E Augello, CM Bellanca… - Infectious Disease …, 2022 - mdpi.com
… The attachment of IL-6 to membrane-IL-6-R (mIL-6R) specifically determines the activation
of a signaling pathway named cis-signaling or the classis mode that mediates host protection …

Integrative pharmacological mechanism of vitamin C combined with glycyrrhizic acid against COVID-19: findings of bioinformatics analyses

R Li, K Wu, Y Li, X Liang, KP Lai… - Briefings in …, 2021 - academic.oup.com
… VC and GA treatment for COVID-19 was associated with elevation of … of the T cell receptor
signaling pathway, regulation of Fc … molecular pathways of VC + GA action against COVID-19. …

Identification of robust protein associations with COVID-19 disease based on five clinical studies

K Suhre, H Sarwath, R Engelke, MU Sohail… - Frontiers in …, 2022 - frontiersin.org
… , comparing key regulatory pathways in COVID-19 patients to … NIH/FDA COVID-19 conference,
the core aim of COVID-19 … is CD40 from the NF-κB signaling pathway, one with the lowest …

[HTML][HTML] SARS-CoV-2 infection triggers phosphorylation: potential target for anti-COVID-19 therapeutics

B Chatterjee, SS Thakur - Frontiers in immunology, 2022 - frontiersin.org
… kinases and signaling pathways can be potential therapeutic targets for anti-COVID-19 drug
… and interconnected signaling proteins have great potential to cure COVID-19 patients and …

[HTML][HTML] COVID-19 virulence in aged patients might be impacted by the host cellular microRNAs abundance/profile

S Fulzele, B Sahay, I Yusufu, TJ Lee, A Sharma… - Aging and …, 2020 - ncbi.nlm.nih.gov
… targeting human miRNAs involved in various age-related signalingCOVID-19 decreased
with aging and underlying conditions. GO and KEGG identified impaired signaling pathway

COVID-19: drug targets and potential treatments

C Gil, T Ginex, I Maestro, V Nozal… - Journal of medicinal …, 2020 - ACS Publications
… the severe disease caused by this coronavirus, COVID-19. In this paper, we … signaling
pathways, resulting in inflammation and initiation of cellular immune response. These pathways

[引用][C] Mechanism of Qingfeipaidu decoction on COVID-19 based on network pharmacology

许冬玉, 许玉龙, 王至婉, 吕雅丽, 朱红磊, 宋婷 - 中药药理与临床, 2020

Hesperetin as an anti-SARS-CoV-2 agent can inhibit COVID-19-associated cancer progression by suppressing intracellular signaling pathways

H Zalpoor, M Bakhtiyari, H Shapourian… - …, 2022 - Springer
… as an anti-COVID-19 agent but also can … signaling pathways in cancer patients with
COVID-19. Therefore, in this review, we attempted to provide evidence demonstrating anti-COVID-19/…

Investigation of COVID-19 comorbidities reveals genes and pathways coincident with the SARS-CoV-2 viral disease

ME Dolan, DP Hill, G Mukherjee, MS McAndrews… - Scientific reports, 2020 - nature.com
signaling pathways that are enriched in COVID-19 … for the interleukin signaling
pathway enrichment we examined the … comorbidities for interleukin signaling pathways (Supplemental …

[HTML][HTML] p38 MAPK inhibition: A promising therapeutic approach for COVID-19

JM Grimes, KV Grimes - Journal of molecular and cellular cardiology, 2020 - Elsevier
pathway, while simultaneously taking advantage of p38 activity to replicate. Therapeutic
inhibition of p38 could therefore attenuate COVID-19 … trials in serious COVID-19 infection. …