Discharge may not be the end of treatment: pay attention to pulmonary fibrosis caused by severe COVID19

C Zhang, Z Wu, JW Li, K Tan, W Yang… - Journal of medical …, 2021 - Wiley Online Library
… of COVID-19 pandemic, the treatment of new cases and critically ill patients is the focus of the
current work. However, COVID-19signaling pathways (TGF- β signal pathway, WNT signal

[HTML][HTML] Overview of COVID-19 inflammatory pathogenesis from the therapeutic perspective

C Lee, WJ Choi - Archives of pharmacal research, 2021 - Springer
… This recognition also leads to the activation of NF-κB and IRF signaling pathways, which
further drives the innate immune system to induce unscheduled cell death following microbial …

[HTML][HTML] The probable role and therapeutic potential of the PI3K/AKT signaling pathway in SARS-CoV-2 induced coagulopathy

MR Khezri, R Varzandeh… - Cellular & Molecular …, 2022 - Springer
… factors have been detected in samples from COVID-19 patients. Here we examine the
role of PI3K/AKT signaling pathways in regulation of these factors’ expression and activity. …

[HTML][HTML] Glycyrrhizic acid for COVID-19: findings of targeting pivotal inflammatory pathways triggered by SARS-CoV-2

W Zheng, X Huang, Y Lai, X Liu, Y Jiang… - Frontiers in …, 2021 - frontiersin.org
… to infer upstream pathway activity from common genes between GA and COVID-19. When
providing a list of genes, the Web server allows inferences about signaling pathways that may …

Metabolic Perturbations and Severe COVID19 Disease: Implication of Molecular Pathways

E Nigro, F Perrotta, R Polito, V D'Agnano… - International Journal …, 2020 - Wiley Online Library
… This is associated with vascular stiffness, hypertrophy, fibrosis, and remodeling mainly
driven through MAPK dependent signaling pathways. Indeed, insulin stimulates secretion and …

[HTML][HTML] Possible therapeutic use of natural compounds against COVID-19

N Khan, X Chen, JD Geiger - Journal of cellular signaling, 2021 - ncbi.nlm.nih.gov
… against SARS-CoV-2 infection and COVID-19 pathogenesis. Naturally existing compounds
(… and mTOR signaling pathways might provide therapeutic relief against COVID-19. Here, we …

[HTML][HTML] Therapeutic mechanism of Toujie Quwen granules in COVID-19 based on network pharmacology

Y Huang, W Zheng, Y Ni, M Li, J Chen, X Liu, X Tan… - BioData mining, 2020 - Springer
… process-signaling pathway”. Our findings suggested that TJQW treatment for COVID-19 was
… - signaling pathway”, we speculated that the active ingredients in the TJQW treatment of …

[HTML][HTML] Looking for pathways related to COVID-19: confirmation of pathogenic mechanisms by SARS-CoV-2–host interactome

F Messina, E Giombini, C Montaldo, AA Sharma… - Cell Death & …, 2021 - nature.com
… KEGG pathway enrichment analysis revealed DNA and RNA … pathways as the most
significant pathways (FDR < 0.01%), as well as signalling pathways and viral infection pathways (…

[HTML][HTML] Inspiration for COVID-19 treatment: Network analysis and experimental validation of baicalin for cytokine storm

J You, H Li, P Fan, X Yang, Y Wei, L Zheng… - Frontiers in …, 2022 - frontiersin.org
… for the treatment of COVID-19 related CS. … for COVID-19 treatment by modulating immune
status and preventing CS. Here, we would predict the potential targets and signaling pathways

Using a System Pharmacology Method to Search for the Potential Targets and Pathways of Yinqiaosan against COVID19

L Cao, X Jia, H He, Z Wang, Y Zhao… - Journal of …, 2022 - Wiley Online Library
… to treat and prevent COVID-19 using network … COVID-19, this paper uses systems
pharmacology techniques and approaches to forecast the possible targets and signaling pathways of …