mTOR inhibition: a double-edged sword in patients with COVID-19?

M Ghasemnejad-Berenji - Human Cell, 2021 - Springer
… the role of cell signaling pathways in the pathogenesis of this … is an important cell signaling
pathway that has important role … inhibitors such as rapamycin against COVID19. However, it …

[HTML][HTML] Protection against COVID-19 injury by qingfei paidu decoction via anti-viral, anti-inflammatory activity and metabolic programming

J Chen, Y Wang, Y Gao, LS Hu, J Yang, J Wang… - Biomedicine & …, 2020 - Elsevier
… -related pathways, endocrine system pathways were also … PPAR signaling pathway and
adipocytokine signaling pathway… damage through PPAR signaling pathway after H1N1 infection, …

Hidden in plain sight: The effects of BCG vaccination in the COVID19 pandemic

EA Toraih, JA Sedhom, TM Dokunmu… - Journal of medical …, 2021 - Wiley Online Library
… -κB signaling pathways. Given the inverse relationship of the specific differentially expressed
gene pathways … may play a protective role against COVID-19 by mounting a nonspecific …

Exploring the treatment of COVID19 with Yinqiao powder based on network pharmacology

H Lin, X Wang, M Liu, M Huang, Z Shen… - Phytotherapy …, 2021 - Wiley Online Library
… of COVID-19 are the TNF signaling pathway, T-cell receptor … signaling pathway. This
study provides a new perspective for discovering potential drugs and mechanisms of COVID-19. …

[HTML][HTML] A hypothesis for the possible role of zinc in the immunological pathways related to COVID-19 infection

A Mayor-Ibarguren, C Busca-Arenzana… - Frontiers in …, 2020 - frontiersin.org
… Legend: A schematic view of the involvement of zinc in various signaling pathways.
Green arrows: zinc-mediated activation. Red T bar arrows: zinc-mediated inhibition. …

Bioinformatics and machine learning approach identifies potential drug targets and pathways in COVID-19

MR Auwul, MR Rahman, E Gov… - Briefings in …, 2021 - academic.oup.com
… of four modules the cytokine–cytokine receptor interaction, the IL-17 signaling pathway
was highly enriched in COVID-19. Viral infectious diseases such as herpes simplex virus 1 …

[HTML][HTML] Network pharmacology study on the mechanism of the Chinese medicine Radix Isatidis (Banlangen) for COVID-19

B Yu, F Lin, H Ning, B Ling - Medicine, 2021 - journals.lww.com
… In summary, Banlangen regulates RAGE, IL-17, TNF, and other signaling pathways to inhibit
inflammation and immune response by acting on PTGS1, PTGS2, NOS2, and other targets, …

[HTML][HTML] … similarities between the lung transcriptomic profiles of COVID-19, COPD, and IPF Patients: a Meta-analysis study of Pathophysiological Signaling Pathways

D Aguilar, A Bosacoma, I Blanco, O Tura-Ceide… - Life, 2022 - mdpi.com
… important activated molecular pathways in the lungs of patients who died of COVID-19, using
… We also compared the molecular pathways triggered in COVID-19 with those triggered in …

[HTML][HTML] The many faces of JAKs and STATs within the COVID-19 storm

AH Grant, A Estrada III, YM Ayala-Marin… - Frontiers in …, 2021 - frontiersin.org
… (JAKs) and Signal Transducers and Activators of … Coronavirus Disease 2019 (COVID-19).
In this report, cytokines found in the storm are discussed in relation to the JAK-STAT pathway

COVID-19: disease pathways and gene expression changes predict methylprednisolone can improve outcome in severe cases

S Draghici, TM Nguyen, LA Sonna, C Ziraldo… - …, 2021 - academic.oup.com
… The chemokine signaling pathway is the second most significantly impacted … In summary,
we describe the inflammatory pathways associated with the cytokine storm found in COVID-19