Efficacy and safety of sofosbuvir/velpatasvir versus the standard of care in adults hospitalized with COVID-19: a single-centre, randomized controlled trial

B Sayad, R Khodarahmi, F Najafi… - Journal of …, 2021 - academic.oup.com
… they may inhibit two coronavirus enzymes. This … sofosbuvir/velpatasvir combination plus
the national standard of care in adult patients hospitalized with moderate to severe COVID-19

Efficacy and safety of the sofosbuvir/velpatasvir combination for the treatment of patients with early mild to moderate COVID-19

V Messina, R Nevola, A Izzi, P De Lucia Sposito… - Scientific Reports, 2022 - nature.com
… that used the combination sofosbuvir/daclastavir (SOF/DCV), the latter of which was very
similar to velpatasvir, in patients with moderate/severe COVID-19 concluded that antiviral …

[PDF][PDF] Editorial–Sofosbuvir/Velpatasvir as a combination with strong potential activity against SARS-CoV2 (COVID-19) infection: how to use direct-acting antivirals as …

A Izzi, V Messina, L Rinaldi… - Eur Rev Med Pharmacol …, 2020 - researchgate.net
… of compounds with therapeutic potential against COVID-195,6. … Sofosbuvir and Velpatasvir,
able to targeting viruses belonging to two or more viral families (as flavivirus and coronavirus

Effect of sofosbuvir-based treatment on clinical outcomes of patients with COVID-19: a systematic review and meta-analysis of randomised controlled trials

CK Hsu, CY Chen, WC Chen, CC Lai, SH Hung… - International Journal of …, 2022 - Elsevier
… /daclatasvir, sofosbuvir/ledipasvir and sofosbuvir/velpatasvir, on the clinical outcomes in
patients with COVID-19… the impact of sofosbuvir-based treatment on the mortality of patients with …

Clinical outcomes of sofosbuvir-based antivirals in patients with COVID-19: a systematic review and meta-analysis of randomized trials

CS Kow, A Javed, D Ramachandram… - Expert Review of Anti …, 2022 - Taylor & Francis
… the use of sofosbuvirvelpatasvir and sofosbuvir alone, respectively, for … of sofosbuvirdaclatasvir
among patients with COVID-19 relative to non-administration of sofosbuvirdaclatasvir

Sofosbuvir as repurposed antiviral drug against COVID-19: why were we convinced to evaluate the drug in a registered/approved clinical trial?

B Sayad, M Sobhani, R Khodarahmi - Archives of medical research, 2020 - Elsevier
… could also be susceptible to sofosbuvir and we were … of sofosbuvir 400 mg (in combination
with velpatasvir 100 mg, as add-on treatment, in addition to standard of care) on the COVID-19

Sofosbuvir/daclatasvir regimens for the treatment of COVID-19: an individual patient data meta-analysis

B Simmons, H Wentzel, S Mobarak… - Journal of …, 2021 - academic.oup.com
… Available evidence suggests that sofosbuvir/daclatasvir improves survival and clinical
recovery in patients with moderate to severe COVID-19. However, the sample size for analysis …

Sofosbuvir and velpatasvir for HCV in patients with decompensated cirrhosis

MP Curry, JG O'Leary, N Bzowej, AJ Muir… - … England Journal of …, 2015 - Mass Medical Soc
sofosbuvirvelpatasvir with or without ribavirin for 12 weeks and with sofosbuvirvelpatasvir
Serious adverse events occurred in 19% of patients who received sofosbuvirvelpatasvir for …

Clinical Effectiveness and Safety of SofosbuvirVelpatasvir as Add-on Treatment for COVID-19 Patients: Study Protocol and Preliminary Data for the Randomized …

B Sayad, M Mehrabi, R Khodarahmi… - Journal of Reports in …, 2021 - journals.lww.com
… the theoretical efficacy of ribavirin and sofosbuvir in the treatment of COVID-19 patients.[ 13
sofosbuvir could be used as treatment against SARS-CoV-2 infection.[ 15 ] Also, velpatasvir

Sofosbuvir and daclatasvir compared with standard of care in the treatment of patients admitted to hospital with moderate or severe coronavirus infection (COVID-19) …

A Sadeghi, A Ali Asgari, A Norouzi… - Journal of …, 2020 - academic.oup.com
… been found to treat COVID-19. The aim of this trial was to assess if the addition of sofosbuvir
and daclatasvir improved clinical outcomes in patients with moderate or severe COVID-19. …