Overview of COVID-19 inflammatory pathogenesis from the therapeutic perspective

C Lee, WJ Choi - Archives of pharmacal research, 2021 - Springer
… Therefore, restoring the SARS-CoV-2-induced RAS imbalance has been suggested as
an ideal clinical approach to slow the early progression of COVID-19 pathogenesis. …

Targeting ACE2 for COVID-19 therapy: opportunities and challenges

H Jia, E Neptune, H Cui - American journal of respiratory cell and …, 2021 - atsjournals.org
… Our proposed strategies for targeting ACE2 in COVID-19 therapy are illustrated in Figure 2.
… In conclusion, ACE2 targeting is an underexplored approach to COVID-19 therapeutics and …

Evaluating primary endpoints for COVID-19 therapeutic trials to assess recovery

DJ Douin, L Siegel, G Grandits, A Phillips… - American journal of …, 2022 - atsjournals.org
… We compared three approaches for defining recovery following a COVID-19 hospitalization:
… days at home (Therapeutics for Inpatients with COVID-19 [TICO] approach), and 3) recovery …

Identification and Development of Therapeutics for COVID-19

HM Rando, N Wellhausen, S Ghosh, AJ Lee… - Msystems, 2021 - Am Soc Microbiol
… , a large number of possible pharmaceutical approaches for … candidate therapeutics
have borne out during COVID-19. … Therefore, one potential approach to reducing COVID-19

Immune-mediated approaches against COVID-19

HF Florindo, R Kleiner, D Vaskovich-Koubi… - Nature …, 2020 - nature.com
… the design of COVID-19 specific therapeutics and vaccines … of these prophylactic and
therapeutic approaches. This Review … -mediated approaches currently explored for COVID-19

A comprehensive overview of proteomics approach for COVID 19: new perspectives in target therapy strategies

R Rana, V Rathi, NK Ganguly - Journal of Proteins and Proteomics, 2020 - Springer
… situations and discusses the proteomics approach towards the COVID-19 dilemma. … therapy
for severe patients remains hypothetical, largely due to limited understanding of COVID 19

Cell therapy strategies for COVID-19: Current approaches and potential applications

MM Zaki, E Lesha, K Said, K Kiaee… - Science …, 2021 - science.org
… in treating severe COVID-19 presentations due to … COVID-19 pathogenesis, respective
areas where cell therapies have potential, and the ongoing 89 cell therapy trials in COVID-19 as …

Therapeutic approaches for COVID-19 based on the interferon-mediated immune responses

P Mosaddeghi, F Shahabinezhad… - … Therapy, 2021 - ingentaconnect.com
… ics tools and a systems biology approach [16]. The obtained results will be validated
through a literature review on SARS, MERS, and COVID-19 to indicate how the IFNmediated …

[HTML][HTML] Hyper-inflammatory responses in COVID-19 and anti-inflammatory therapeutic approaches

H Choi, EC Shin - BMB reports, 2022 - ncbi.nlm.nih.gov
COVID-19 and novel exosome-based therapeuticsCOVID-19. We also highlight the
potential roles of exosomes as novel anti-inflammatory therapeutics for the treatment of COVID-19. …

An overview of key potential therapeutic strategies for combat in the COVID-19 battle

G Das, S Ghosh, S Garg, S Ghosh, A Jana, R Samat… - RSC …, 2020 - pubs.rsc.org
… article is to provide a brief collective overview of the recent status of therapeutics advances
and approaches, and their current state of implementation for the management of COVID-19. …