Current status of potential therapeutic candidates for the COVID-19 crisis

J Zhang, B Xie, K Hashimoto - Brain, behavior, and immunity, 2020 - Elsevier
… In this review, we summarize the potential therapeutic candidates under development for
COVID-19 based on clinical trials and describe their potential mechanisms of action (Fig. 2 and …

[HTML][HTML] COVID-19: The immune responses and clinical therapy candidates

S Zhand, M Saghaeian Jazi, S Mohammadi… - International journal of …, 2020 - mdpi.com
… The outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection
Coronavirus disease-19 (COVID-19) is an illness caused by this novel coronavirus and can …

Systems and clinical pharmacology of COVID-19 therapeutic candidates: a clinical and translational medicine perspective

S Perazzolo, L Zhu, W Lin, A Nguyen… - Journal of Pharmaceutical …, 2021 - Elsevier
… million have died due to COVID-19 disease progression. COVID-19 presents flu-like symptoms
… Although social distancing reduces transmissibility, COVID-19 vaccines and therapeutics

[HTML][HTML] Pathophysiology and potential therapeutic candidates for COVID-19: a poorly understood arena

A Samaddar, M Grover, VL Nag - Frontiers in pharmacology, 2020 - frontiersin.org
… and summarizes the potential treatment candidates, which can provide guidance in … The
major proposed therapeutic candidates that seem promising for the treatment of COVID-19 are …

[PDF][PDF] Review of Therapeutic Candidates for the New Corona Virus Disease (COVID-19)

E Behboudi, V Hamidi-Sofiani… - Razi Journal of Medical …, 2020 - researchgate.net
… Although there is no approved drug or vaccine for COVID-19, … select appropriate laboratory
and clinical candidate drugs (4). … to review therapeutic candidates for the emerging COVID-19

COVID-19: A review of therapeutic strategies and vaccine candidates

V Izda, MA Jeffries, AH Sawalha - Clinical Immunology, 2021 - Elsevier
… overview of COVID-19, along with an introduction to the biology of the SARS-CoV-2 virus.
Then, we will describe in detail the vaccine candidates and various therapeutic strategies, …

[HTML][HTML] Optimizing COVID19 candidate therapeutics: thinking without borders

CR Rayner, PF Smith, K Hershberger… - Clinical and …, 2020 - ncbi.nlm.nih.gov
… With COVID19 vaccine availability likely 12–18 months away, there is an immediate need
to examine COVID19 therapeutic candidate options, which could arrive on the scene more …

[HTML][HTML] Optimal COVID-19 therapeutic candidate discovery using the CANDO platform

W Mangione, Z Falls, R Samudrala - Frontiers in Pharmacology, 2022 - frontiersin.org
COVID-19, and were validated by Ennaid Therapeutics, LLC in a propreitary study. The
compounds exclusive to the patent are not included in the list of the 51 validated actives and are …

[HTML][HTML] Potential therapeutic options for COVID-19: current status, challenges, and future perspectives

C Sarkar, M Mondal, M Torequl Islam… - Frontiers in …, 2020 - frontiersin.org
… We selected a total of 72 most current or ongoing clinical trials of the COVID-19 drug candidates
… to discover and develop antiviral drug candidates for COVID-19 (Table 1 and Figure 2). …

[HTML][HTML] Strategies and challenges to develop therapeutic candidates against COVID-19 pandemic

R Bhatia, SS Ganti, RK Narang… - The Open Virology …, 2020 - benthamopen.com
… order to develop a suitable therapeutic candidate against COVID-19. The repurposed drugs
… on therapeutic agents and vaccines for COVID-19 and related human coronavirus diseases. …