Weathering the cytokine storm in COVID-19: therapeutic implications

G Iannaccone, R Scacciavillani, MG Del Buono… - Cardiorenal …, 2020 - karger.com
… In the quest for more effective COVID-19 therapeutic strategies, accumulating evidence …
the pathogenesis of progressive hypoxia in patients with COVID-19. While the initial results with …

[HTML][HTML] Endothelial dysfunction in COVID-19: Current findings and therapeutic implications

MP Nägele, B Haubner, FC Tanner, F Ruschitzka… - Atherosclerosis, 2020 - Elsevier
Coronavirus disease 2019 (COVID-19) increases the risk of … dysfunction with COVID-19
and its therapeutic implications. … that increase risk for severe COVID-19 such as hypertension, …

The emerging threat of (micro) thrombosis in COVID-19 and its therapeutic implications

JD McFadyen, H Stevens, K Peter - Circulation research, 2020 - Am Heart Assoc
… Finally, we will use this data to explore available therapeutic approaches for the prevention
and treatment of COVID-19-associated thrombosis. Given the relative lack of data to date …

[HTML][HTML] Understanding the immunopathogenesis of COVID-19: Its implication for therapeutic strategy

Y Shimizu - World journal of clinical cases, 2020 - ncbi.nlm.nih.gov
… could influence the outcome of coronavirus disease 2019 (COVID-19). SARS-… Therapeutic
strategy should therefore be based on viral kinetics and the immunopathology of COVID-19

COVID-19 and immunothrombosis: Pathophysiology and therapeutic implications

MS Lim, S Mcrae - Critical Reviews in Oncology/Hematology, 2021 - Elsevier
… Various mechanisms have been proposed to explain the coagulopathy caused by COVID-19, …
, clinical, laboratory and therapeutic implications of COVID-19 coagulopathy. A summary of …

[HTML][HTML] A nicotinic hypothesis for Covid-19 with preventive and therapeutic implications

JP Changeux, Z Amoura… - Comptes …, 2020 - comptes-rendus.academie-sciences …
… of Covid-19 infection and might represent a target for the prevention and control of Covid-19
Covid-19 et puisse représenter une cible pour la prévention et le contrôle de l’infection. …

Deep immune profiling of COVID-19 patients reveals distinct immunotypes with therapeutic implications

…, AC Huang, LA Vella, UPenn COVID Processing Unit†… - Science, 2020 - science.org
… respiratory syndrome coronavirus 2 (… COVID-19 is currently poorly understood, and defining
the nature of immune responses during acute COVID-19 could help identify therapeutics

Therapeutic implications of ongoing alveolar viral replication in COVID-19

D McGonagle, MF Kearney, A O'Regan… - The Lancet …, 2022 - thelancet.com
… We focus on patients with moderate-to-severe COVID-19, rather than on those with mild
disease who do not require oxygen therapy or those with critical disease undergoing prolonged …

Therapeutic implications of COVID-19 for the interventional cardiologist

M Kelham, FA Choudry, S Hamshere… - … and Therapeutics, 2021 - journals.sagepub.com
… on the important therapeutic implications of COVID-19 for … presentations seen in COVID-19
positive patients and the … in patients with COVID-19 and acute coronary syndromes. …

Therapeutic strategies for COVID-19: progress and lessons learned

G Li, R Hilgenfeld, R Whitley, E De Clercq - Nature Reviews Drug …, 2023 - nature.com
… anti-coronavirus activities. We also discuss the lessons learned from COVID-19 and other
infectious diseases with regard to drug repurposing strategies, pan-coronavirus drug targets, …