Drug repurposing using computational methods to identify therapeutic options for COVID-19

S Mahdian, A Ebrahim-Habibi, M Zarrabi - Journal of Diabetes & Metabolic …, 2020 - Springer
… Unfortunately, researchers could not find a registered therapy to treat the infection related to
… to identify therapeutic options for COVID-19. For this purpose, five proteins of COVID-19 (3-…

Endothelial dysfunction in COVID-19: potential mechanisms and possible therapeutic options

MC Pelle, I Zaffina, S Lucà, V Forte, V Trapanese… - Life, 2022 - mdpi.com
… There is no certain explanation for this systemic COVID-19 … in severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) … in developing the severe form of COVID-19, in this review, …

Therapeutic options and critical care strategies in covid-19 patients; where do we stand in this battle?

S Afaghi, FE Tarki, FS Rahimi, SSN Irvani… - School of Medicine …, 2020 - journals.sbmu.ac.ir
… receptors, has been the first FDA-approved therapeutic agent for … therapeutic option for
severe or critical cases of COVID-19 with increased levels of IL-6 in some of the major COVID-19

COVID-19: Therapeutics and interventions currently under consideration

RB McFee - Disease-a-Month, 2020 - Elsevier
… virology of COVID-19 may provide multiple potential target points for antiviral therapy, and …
clinical indications were studied for repurposing against COVID-19, which we highlight, again …

Current options in the treatment of COVID-19: a review

A Teimury, E Mahmoodi Khaledi - Risk Management and …, 2020 - Taylor & Francis
… Also, due to the COVID-19 pandemic and high prevalence … COVID-19 patients. In this
review, we collected information about the most widely used drugs to treat COVID-19 (coronavirus

COVID-19 and rheumatoid arthritis crosstalk: emerging association, therapeutic options and challenges

S Dewanjee, R Kandimalla, RS Kalra, C Valupadas… - Cells, 2021 - mdpi.com
… for anti-rheumatic drugs in the COVID-19 setting was presented for better clinical …
COVID-19 and RA crosstalk and their mechanistic overlaps, challenges, and therapeutic options

COVID-19: therapeutic approaches description and discussion

GG Trindade, SMC Caxito, AREO Xavier… - Anais da Academia …, 2020 - SciELO Brasil
… An important aspect to consider is that the medications currently proposed have the advantage
of already being used as therapeutic options for other diseases. Consequently, these are …

Characteristics of the coronavirus disease 2019 and related therapeutic options

B Huang, R Ling, Y Cheng, J Wen, Y Dai… - Molecular Therapy …, 2020 - cell.com
… treatment of the emerging COVID-19. Finally, we summarize clinical trials of some potential
therapeutic drugs and the … This review provides some insights for the treatment of COVID-19. …

[HTML][HTML] Off‐target ACE2 ligands: Possible therapeutic option for CoVid19?

S Brogi, V Calderone - British journal of clinical pharmacology, 2020 - ncbi.nlm.nih.gov
… SARS-Cov-2 (CoVid-19) is responsible for several thousand … positive effects observed in
coronavirus patients who showed … in the most serious cases of CoVid-19. 6 ACE2 is located on …

[HTML][HTML] Recent knowledge in favor of remdesivir (GS-5734) as a therapeutic option for the COVID-19 infections

S Saqrane, MA El Mhammedi, S Lahrich… - Journal of Infection and …, 2021 - Elsevier
… An emerging potential therapeutic approach … COVID-19 by interfering with key steps in the
virus replication cycle. It is considered a therapeutic option to be evaluated against COVID-19, …