Therapeutic targets and interventional strategies in COVID-19: mechanisms and clinical studies

YW Zhou, Y Xie, LS Tang, D Pu, YJ Zhu… - … and targeted therapy, 2021 - nature.com
… of COVID-19, the therapeutic targets and interventions of COVID-19 have been classified into
target virus” and “target host… A comprehensive analysis of the therapeutic targets has been …

Precision therapeutic targets for COVID-19

ZA Krumm, GM Lloyd, CP Francis, LH Nasif… - Virology journal, 2021 - Springer
coronavirus 2 (SARS-CoV-2) emerged as a novel pathogen that causes coronavirus disease
2019 (COVID-19). … and clinical drugs that precisely target three different, essential steps of …

Origin, potential therapeutic targets and treatment for coronavirus disease (COVID-19)

MS Nadeem, MA Zamzami, H Choudhry, BN Murtaza… - Pathogens, 2020 - mdpi.com
… The ongoing episode of coronavirus disease 19 (COVID-19) has imposed a serious threat
… The causative agent of COVID-19 is a novel coronavirus known as SARS-CoV-2. The virus …

Therapeutic targets and potential agents for the treatment of COVID19

Y Wu, Z Li, YS Zhao, YY Huang… - Medicinal Research …, 2021 - Wiley Online Library
… for the treatment of COVID-19, several therapeutics and drugs … is to summarize three
therapeutic targets (proteases: RNA-… for further drug discovery to combat COVID-19. Both M pro …

COVID19 metabolism: Mechanisms and therapeutic targets

T Wang, Y Cao, H Zhang, Z Wang, CH Man… - MedComm, 2022 - Wiley Online Library
… Here, we summarized the current understanding of the hallmarks of COVID19 metabolism.
… to uncover new therapeutic targets. The efficacy of metabolic inhibitors against COVID19 is …

Endoplasmic reticulum as a potential therapeutic target for covid-19 infection management?

A Sureda, J Alizadeh, SF Nabavi… - European journal of …, 2020 - Elsevier
… and innate immunity in Coronavirus infected cells. Hence, … as potential therapeutics for
controlling Covid 19 infection. … therapeutic effects of targeting autophagy and replication in …

Rheumatologists' perspective on coronavirus disease 19 (COVID-19) and potential therapeutic targets

DP Misra, V Agarwal, AY Gasparyan, O Zimba - Clinical rheumatology, 2020 - Springer
therapy. In this article, we provide the perspectives of a rheumatologist on COVID-19, …
We also discuss potential therapeutic targets for management of COVID-19, some of which …

Furin: a potential therapeutic target for COVID-19

C Wu, M Zheng, Y Yang, X Gu, K Yang, M Li, Y Liu… - Iscience, 2020 - cell.com
COVID-19 broke out in the end of December 2019 and is still spreading rapidly, which has
been listed as an international concerning public health emergency. We found that the Spike …

[HTML][HTML] Databases for the targeted COVID19 therapeutics

Y Wang, F Li, Y Zhang, Y Zhou, Y Tan… - British Journal of …, 2020 - ncbi.nlm.nih.gov
… every target, its relevance to COVID19therapeutic target, with particular focus on the
target's relevance to the regulations of disease progression/life‐threatening symptom of COVID19

COVID-19 associated complications and potential therapeutic targets

JD Monpara, SJ Sodha, PK Gupta - European Journal of Pharmacology, 2020 - Elsevier
… conditions, several targets are identified to prevent, treat or mange COVID-19. The therapeutic
targets are presented in a manner to represent the events in COVID-19 (ie virus entry and …