… coronavirus 2 (SARS-CoV-2) emerged as a novel pathogen that causes coronavirus disease 2019 (COVID-19). … and clinical drugs that precisely target three different, essential steps of …
C Gil, T Ginex, I Maestro, V Nozal… - Journal of medicinal …, 2020 - ACS Publications
… (234) NSC61610 (Figure 20) induces lanthionine synthetase C-like 2 (LANCL2), a therapeutictarget for treating infectious diseases such as IFV-A infection. (235) The Ligustrum …
Y Wu, Z Li, YS Zhao, YY Huang… - Medicinal research …, 2021 - Wiley Online Library
… for the treatment of COVID-19, several therapeutics and drugs … is to summarize three therapeutictargets (proteases: RNA-… for further drug discovery to combat COVID-19. Both M pro …
G Li, R Hilgenfeld, R Whitley, E De Clercq - Nature Reviews Drug …, 2023 - nature.com
… DUB and DUB-like proteases are under investigation as therapeutictargets for other human diseases, but no inhibitors of these proteins have yet been approved 70 . Future …
… The ongoing episode of coronavirus disease 19 (COVID-19) … The causative agent of COVID-19 is a novel coronavirus … -CoV, CoV-pangolin, and the coronavirus the from horseshoe bat. …
T Wang, Y Cao, H Zhang, Z Wang, CH Man… - MedComm, 2022 - Wiley Online Library
… Here, we summarized the current understanding of the hallmarks of COVID‐19 metabolism. … to uncover new therapeutictargets. The efficacy of metabolic inhibitors against COVID‐19 is …
… therapy. In this article, we provide the perspectives of a rheumatologist on COVID-19, … We also discuss potential therapeutictargets for management of COVID-19, some of which …
JKY Yap, M Moriyama, A Iwasaki - The Journal of Immunology, 2020 - journals.aai.org
… coronavirus 2, we highlight the importance of the inflammasome pathway. We discuss available pharmaceutical agents that target … target for the treatment of severe coronavirus disease …
… Suppression of ACE2 in COVID-19 may be harmful and can lead to overstimulation of the … of COVID-19 disease, as well as a framework for developing novel therapeutictargets. The …