[HTML][HTML] COVID-19: therapeutics and their toxicities

MA Chary, AF Barbuto, S Izadmehr, BD Hayes… - Journal of Medical …, 2020 - Springer
… alcohol could prevent coronavirus infection [… therapeutics against SARS-CoV-19. We intend
for this review to familiarize readers with the toxicities of potential therapeutics for COVID-19

[HTML][HTML] Therapeutics for COVID-19

SS Toussi, JL Hammond, BS Gerstenberger… - Nature …, 2023 - nature.com
target host-driven COVID-19 symptoms, are also in use. We highlight the development of
COVID-19 … antigens as therapeutic targets. The RNA genome replication provides an avenue of …

[HTML][HTML] ACE2 as a therapeutic target for COVID-19; its role in infectious processes and regulation by modulators of the RAAS system

V Michaud, M Deodhar, M Arwood… - Journal of Clinical …, 2020 - mdpi.com
coronavirus disease 2019 (COVID-19) pandemic [4,5]. At the time this review was written (24
June 2020), COVID-19 … Soon after its outbreak, clinical features associated with COVID-19

[HTML][HTML] An overview of key potential therapeutic strategies for combat in the COVID-19 battle

G Das, S Ghosh, S Garg, S Ghosh, A Jana, R Samat… - RSC …, 2020 - pubs.rsc.org
… 3 represents the viral life cycles and potential therapeutic targets that can be used to treat
COVID-19 infection. The list of drugs to deal with the same is given in Table 1. …

Recent advances in small-molecular therapeutics for COVID-19

L Zhong, Z Zhao, X Peng, J Zou… - Precision Clinical …, 2022 - academic.oup.com
… and repurposed for COVID-19 clinical therapy based on … authorization or approved for
COVID-19 therapy in many countries … hope for us to finally conquer COVID-19. In this account, we …

[HTML][HTML] Transcription factor Nrf2 as a potential therapeutic target for prevention of cytokine storm in COVID-19 patients

RA Zinovkin, OA Grebenchikov - Biochemistry (Moscow), 2020 - Springer
… infect endothelial and other target cells in kidneys, … COVID-19 infection multiple organ failure
associated with hyperactivation of the immune system is observed. Patients with COVID-19

Current treatments and therapeutic options for COVID-19 patients: a systematic review

E Mehraeen, Z Najafi, B Hayati… - … -Drug Targets  …, 2022 - ingentaconnect.com
… , one cohort study), and 19 published clinical trials. Review of … therapies used to treat
COVID-19 patients. Conclusion: In the … effective therapy for accelerating the recovery of COVID-19

[HTML][HTML] Role of myeloid-derived suppressor cells in viral respiratory infections; Hints for discovering therapeutic targets for COVID-19

K Koushki, M Salemi, SM Miri, Y Arjeini… - Biomedicine & …, 2021 - Elsevier
… , MDSCs are accumulated in COVID-19 patients, in particular … effects on severe forms of
COVID-19, suggesting the targeting … and therapeutic approaches, especially against COVID-19

SARS-CoV-2 RNA-dependent RNA polymerase as a therapeutic target for COVID-19

I Vicenti, M Zazzi, F Saladini - Expert Opinion on Therapeutic …, 2021 - Taylor & Francis
… East respiratory syndrome coronavirus (MERS-CoV) in 2012. Coronavirus disease 2019 (COVID-19)
is an acute respiratory infection disease caused by a novel coronavirus (2019-…

Protease-activated receptor 1 as a potential therapeutic target for COVID-19

ES Rovai, T Alves… - Experimental Biology and …, 2021 - journals.sagepub.com
therapeutics yet. Here we will review some insights with regards to the pathogenesis of
COVID-19 in … consider the protease-activated receptor 1 (PAR1) as a potential therapeutic target. …