K Janiuk, E Jabłońska, M Garley - Cells, 2021 - mdpi.com
… traps (NETs) playing a significant role in the mechanism of combating pathogens, in the pathogenesis of COVID-19. … on the severe course of COVID-19 in patients with concurrent …
… histone H3, and DNA are seen in COVID-19 patient sera [18, 19]. While treatment of naive … COVID-19 patients stimulated NETosis [19] and NETs are seen in lung tissue of COVID-19 …
EA Middleton, XY He, F Denorme… - Blood, The Journal …, 2020 - ashpublications.org
… In this study, we provide clinical evidence that increased NET formation correlates with COVID-19–related ARDS and is a potential biomarker for disease severity. We also demonstrate …
N Kinnare, JS Hook, PA Patel, NL Monson… - Inflammation, 2022 - Springer
… Treatment options for COVID-19 are limited and primarily … NET formation in the lungs of severely ill COVID-19 patients, … We hypothesized that the NET formation potential of circulating …
BJ Barnes, JM Adrover, A Baxter-Stoltzfus… - Journal of Experimental …, 2020 - rupress.org
… (NETs)—may contribute to organ damage and mortality in COVID-19. We show lung … succumbed to COVID-19. We discuss prior reports linking aberrant NET formation to pulmonary …
M Pastorek, M Dúbrava, P Celec - Frontiers in Immunology, 2022 - frontiersin.org
… has been shown and proved, the causes of NETs formation are unclear. The aim of … formation in severe COVID-19 and to discuss potential treatment options targeting NETs formation of …
M Leppkes, J Knopf, E Naschberger, A Lindemann… - …, 2020 - thelancet.com
… Here, we show that severe COVID-19 is characterized by a highly pronounced formation of neutrophil extracellular traps (NETs) inside the micro-vessels. Intravascular aggregation of …
… Different studies proposed that NETs formation in Covid-19 might be the potential cause of venous and arterial thrombo-embolism due to vasculitis and immune-mediated mechanism […
N de Buhr, M von Köckritz-Blickwede - MBio, 2021 - Am Soc Microbiol
… for severe COVID-19 to degrade NETs. Based on the described NET formation in COVID-19 … alfa (Pulmozyme) for the treatment of severe COVID-19 ARDS (44). Interestingly, local …