Baricitinib versus dexamethasone for adults hospitalised with COVID-19 (ACTT-4): a randomised, double-blind, double placebo-controlled trial

CR Wolfe, KM Tomashek, TF Patterson… - The lancet respiratory …, 2022 - thelancet.com
Background Baricitinib and dexamethasone have randomised trials supporting their use for
the treatment of patients with COVID-19. We assessed the combination of baricitinib plus …

[HTML][HTML] Covid-19 treatment-induced neuropsychiatric adverse effects

CAC García, EBA Sánchez, DH Huerta… - General Hospital …, 2020 - ncbi.nlm.nih.gov
… of the now termed coronavirus disease (COVID-19), which can … high-dose corticosteroid
treatment, as occurs in COVID-19, may … such as delirium have been rarely reported in adults [6]. …

COVID-19 treatment options: a difficult journey between failed attempts and experimental drugs

A Bartoli, F Gabrielli, T Alicandro, F Nascimbeni… - Internal and emergency …, 2021 - Springer
… The Food and Drug Administration has authorized Remdesivir compassionate use for the
treatment of adults and children with severe COVID-19 disease who do not respond to other …

A systematic review assessing the under-representation of elderly adults in COVID-19 trials

V Prendki, N Tau, T Avni, M Falcone, A Huttner… - BMC geriatrics, 2020 - Springer
… The search yielded 2191 RCTs; after applying eligibility criteria, 12 full-text trials assessing
various treatment options for COVID-19 were included (Fig. 1). Risk of bias assessment of …

Baricitinib reduces 30‐day mortality in older adults with moderate‐to‐severe COVID19 pneumonia

P Abizanda, JM Calbo Mayo… - Journal of the …, 2021 - Wiley Online Library
… mortality rate in adults aged 70 years or older hospitalized by COVID-19 pneumonia.
Baricitinib could be a good treatment in older adult populations with severe COVID-19, and could …

[HTML][HTML] COVID-19 sequelae in adults aged less than 50 years: A systematic review

S Willi, R Lüthold, A Hunt, NV Hänggi, D Sejdiu… - Travel medicine and …, 2021 - Elsevier
… of all intermediate and long-term COVID-19 sequelae affecting formerly healthy adults. …
adults aged 18–50 years as they make up the majority of the working population. COVID-19 in …

COVID-19 treatment: close to a cure? A rapid review of pharmacotherapies for the novel coronavirus (SARS-CoV-2)

Y Song, M Zhang, L Yin, K Wang, Y Zhou… - International journal of …, 2020 - Elsevier
… The selection of treatments in this review is based on the 7th edition of the ‘COVID-19
diagnosis and treatment guideline’ issued by the National Health Commission (NHC) of the …

Methylprednisolone in adults hospitalized with COVID-19 pneumonia: An open-label randomized trial (GLUCOCOVID)

L Corral-Gudino, A Bahamonde… - Wiener klinische …, 2021 - Springer
… patients over 60 years with severe COVID 19 (with SpO2 ≤ 94… We did not find evidence of
interaction between treatment … study is underpowered to detect treatment differences in the ITT …

[HTML][HTML] Effect of ivermectin on time to resolution of symptoms among adults with mild COVID-19: a randomized clinical trial

E López-Medina, P López, IC Hurtado, DM Dávalos… - Jama, 2021 - jamanetwork.com
… Can you clarify how many days on average elapsed between the diagnosis of COVID-19
and the beginning of treatment with ivermectin? It seems as if 2 "bonus" days are not bad at all. …

Antiviral treatment of COVID-19

S Yavuz, S Ünal - Turkish journal of medical sciences, 2020 - journals.tubitak.gov.tr
… effective antiviral treatment for COVID-19. Although most of the COVID-19 patients have mild
… In a prospective randomized trial of 30 adults with COVID-19 in China, 15 patients treated …