COVID-19: immunopathogenesis and Immunotherapeutics

L Yang, S Liu, J Liu, Z Zhang, X Wan… - … and targeted therapy, 2020 - nature.com
cytokines, IL-6 is a key mediator for the development of cytokine storm in COVID-19 cases. …
, indicating that they can potentially be used for treating patients with COVID-19. Nevertheless…

[HTML][HTML] Cytokine storm in novel coronavirus disease (COVID-19): expert management considerations

Y Mehta, SB Dixit, KG Zirpe… - … Society of Critical Care …, 2020 - ncbi.nlm.nih.gov
… about the management of cytokine storm in COVID-19. From … can be beneficial in managing
cytokine storm. The use of … regarding their use for cytokine storm in COVID-19 is limited. …

Calming the cytokine storm in COVID-19

RQ Cron, R Caricchio, WW Chatham - Nature medicine, 2021 - nature.com
IL-6 blockade with monoclonal antibodies to either IL-6 or the IL-6 receptor. There have
been many reported clinical trials exploring inhibition of IL-6 for the treatment of COVID-19; no …

COVID-19 cytokine storm: what is in a name?

PA Nigrovic - Annals of the rheumatic diseases, 2021 - ard.bmj.com
… It is tempting to conclude that patients with “COVID-CS” should be treated for cytokine
storm. However, randomised controlled trials (RCTs) of interleukin (IL)-6 blockade for severe …

Capturing cytokines with advanced materials: a potential strategy to tackle COVID19 cytokine storm

QF Meng, R Tian, H Long, X Wu, J Lai… - Advanced …, 2021 - Wiley Online Library
… It is anticipated that this work will provide insights on the development of novel therapeutics
toward efficacious management of COVID-19 cytokine storm and other inflammatory …

The cytokine storm in COVID-19: Further advances in our understanding the role of specific chemokines involved

F Coperchini, L Chiovato, G Ricci, L Croce… - Cytokine & Growth …, 2021 - Elsevier
… Of note some clinical data suggest that treatment with the CCR5 blocking antibody (ie …
strategy for COVID 19 treatment [56]. More specifically, Patterson et al., reported that treatment with …

Calming the storm: natural immunosuppressants as adjuvants to target the cytokine storm in COVID-19

AE Peter, BV Sandeep, BG Rao… - Frontiers in …, 2021 - frontiersin.org
treatment of COVID-19, downregulation of the cytokine storm … to suppress the cytokine storm
associated with inflammation … the cytokine storm syndrome observed in COVID-19 patients …

Can natural polyphenols help in reducing cytokine storm in COVID-19 patients?

G Giovinazzo, C Gerardi, C Uberti-Foppa, L Lopalco - Molecules, 2020 - mdpi.com
treatment of critically unwell patients with COVID-19. This review demonstrates that, at least
until the time of writing this paper, there is no proven cytokine blocking agents for COVID-19, …

Basic predictive risk factors for cytokine storms in COVID-19 patients

SG Shcherbak, AY Anisenkova, SV Mosenko… - Frontiers in …, 2021 - frontiersin.org
… Our results provide a justification for a treatment strategy with an early onset of proactive
anti-inflammatory therapy and anti-COVID-19 convalescent plasma in patients at a high risk for …

Cytokine storm in COVID-19: Potential therapeutics for immunomodulation

MM Rana - Journal of Research in Clinical Medicine, 2020 - library.2pressrelease.co.in
… candidates for the cytokine release syndrome (CRS) treatment in COVID-19 infection.
This review was conducted to discuss all the possible signalling pathways involved in …