Prospective roles of tumor necrosis factor-alpha (TNF-α) in COVID-19: prognosis, therapeutic and management

Z Mohd Zawawi, J Kalyanasundram… - International journal of …, 2023 - mdpi.com
… In COVID-19, TNF-α-mediated … with COVID-19 morbidity and mortality. In addition, this
review also proposes the potential of TNF-α as a biomarker for the prognosis of severe COVID-19

[HTML][HTML] Role of tumor necrosis factor-α in the mortality of hospitalized patients with severe and critical COVID-19 pneumonia

F Jia, G Wang, J Xu, J Long, F Deng, W Jiang - Aging (Albany NY), 2021 - ncbi.nlm.nih.gov
COVID-19. This study aims to characterize serum cytokines of patients with severe or critical
COVID-19… Compared with patients in severe COVID-19, those who in critical COVID-19 had …

CD4+ T-Cell Dysfunction in Severe COVID-19 Disease Is Tumor Necrosis Factor-α/Tumor Necrosis Factor Receptor 1–Dependent

I Popescu, ME Snyder, CJ Iasella… - American Journal of …, 2022 - atsjournals.org
… Lymphopenia is common in severe coronavirus disease (COVID-19), and here we show it is
… -α (tumor necrosis factor-α) in CD4 + T cells from patients with severe COVID-19 and further …

… between tumor necrosis factor inhibitors and the risk of hospitalization or death among patients with immune-mediated inflammatory disease and COVID-19

Z Izadi, EJ Brenner, SK Mahil, N Dand… - JAMA network …, 2021 - jamanetwork.com
… for the distribution of covariates in all patients with COVID-19, based on data of two health
care systems with systematic report of COVID-19. However, this analysis was limited to …

… levels of interleukin-6 and interleukin-10, but not tumor necrosis factor-alpha, as potential biomarkers of severity and mortality for COVID-19: systematic review with …

W Udomsinprasert, J Jittikoon… - Journal of clinical …, 2021 - Springer
COVID-19, thus highlighting its potential as a biomarker and therapeutic target for COVID-19. …
cytokines with severity and mortality of COVID-19 by systematic review and meta-analysis. …

Clinical outcomes of COVID-19 in patients taking tumor necrosis factor inhibitors or methotrexate: a multicenter research network study

A Yousaf, S Gayam, S Feldman, Z Zinn… - Journal of the American …, 2021 - Elsevier
tumor necrosis factor inhibitors (TNFis) or methotrexate are at increased risk of COVID-19–…
given limitations of COVID-19 confirmatory testing, although COVID-19–specific diagnoses …

Trials of anti-tumour necrosis factor therapy for COVID-19 are urgently needed

M Feldmann, RN Maini, JN Woody, ST Holgate… - The Lancet, 2020 - thelancet.com
… the potential of anti-tumor necrosis factor (TNF) therapy to inhibit development of a cytokine
storm in patients with coronavirus disease 2019 (COVID-19). Following this Comment, I write …

Tumor necrosis factor inhibitors are associated with a decreased risk of COVID19‐associated hospitalization in patients with psoriasis—A population‐based cohort …

K Kridin, Y Schonmann, G Damiani… - Dermatologic …, 2021 - Wiley Online Library
… of coronavirus disease 2019 (COVID-19) and its complications among patients with psoriasis
treated by tumor necrosis … We aimed to assess the risk of COVID-19 infection, COVID-19-…

TNFRSF1B and TNF Variants Are Associated With Differences in Levels of Soluble Tumor Necrosis Factor Receptors in Patients With Severe COVID-19

I Fricke-Galindo, I Buendía-Roldán… - The Journal of …, 2022 - academic.oup.com
… of tumor necrosis factor-α (TNF-α) and its receptors in coronavirus disease 2019 (COVID-19
(rs1061622 and rs3397) variants with COVID-19 severity, assessed as invasive mechanical …

Regulated necrosis in COVID-19: A double-edged sword

C Sun, Y Han, R Zhang, S Liu, J Wang… - Frontiers in …, 2022 - frontiersin.org
… Inflammatory mediators such as IL-2, IL-6, and tumor necrosis factor (TNF) are also infiltrated
by inflammatory cells into the lungs due to increased production, destroying lung structure (…