BF Haynes, L Corey, P Fernandes, PB Gilbert… - Science translational …, 2020 - science.org
… In addition, no serious safety signals have been reported from initial phase 1 trials of COVID-19vaccine candidates, with the caveat that the number of vaccinees who have been …
P Krause, TR Fleming, I Longini, AM Henao-Restrepo… - The Lancet, 2020 - thelancet.com
… , and reliable evaluation of many candidate vaccines against COVID-19. There is a danger … introduction of a COVID-19vaccine could lead to widespread deployment of a vaccine that is …
… of COVID-19vaccines will seriously affect the ongoing phases 2 and 3 randomised placebo-controlled trials assessing SARS-CoV-2 vaccine … and future trials of other COVID-19 …
JH Kim, F Marks, JD Clemens - Nature medicine, 2021 - nature.com
… of COVID-19vaccine efficacy in clinical trials by several … for the next steps to ensure vaccination of the global population is … doses of high-quality vaccines, support for vaccine purchase, …
DV Mehrotra, HE Janes, TR Fleming… - Annals of internal …, 2021 - acpjournals.org
… on study endpoints in COVID-19vaccine efficacy trials. First, … comparison of the efficacy of vaccine candidates, overall and … COVID-19 as well as assessment of the longer-term vaccine …
M Makoni - The Lancet Respiratory Medicine, 2020 - thelancet.com
… -CoV2373 vaccine candidate or other COVID-19vaccines in African … trial, also led by Madhi, of a COVID-19vaccine in South Africa commenced on June 23, which was the first vaccine …
… A 69-year old receives a COVID-19vaccine in a Phase 3 trial. It is important to understand how different groups respond to COVID-19vaccines to establish the most effective …
… Although much of this focus is on trials in the United States, the COVID-19 Prevention Networks established under the ACTIV program have a global focus, and coordination with the …
TT Le, JP Cramer, R Chen, S Mayhew - Nat Rev Drug Discov, 2020 - nature.com
… Possible end points for consideration in COVID-19vaccinetrials include clinical disease of … the trial population is of key importance for advanced-stage COVID-19vaccinetrials. The …