[HTML][HTML] Adverse events reported from COVID-19 vaccine trials: a systematic review

RJ Kaur, S Dutta, P Bhardwaj, J Charan… - Indian Journal of Clinical …, 2021 - Springer
COVID-19 vaccine trials”. Out of which 52 were full texts of clinical trials assessing the safety
of COVID-19 vaccines… of eleven clinical trials on COVID-19 vaccines were published [3]. The …

Prospects for a safe COVID-19 vaccine

BF Haynes, L Corey, P Fernandes, PB Gilbert… - Science translational …, 2020 - science.org
… In addition, no serious safety signals have been reported from initial phase 1 trials of
COVID-19 vaccine candidates, with the caveat that the number of vaccinees who have been …

[HTML][HTML] COVID-19 vaccine trials should seek worthwhile efficacy

P Krause, TR Fleming, I Longini, AM Henao-Restrepo… - The Lancet, 2020 - thelancet.com
… , and reliable evaluation of many candidate vaccines against COVID-19. There is a danger
… introduction of a COVID-19 vaccine could lead to widespread deployment of a vaccine that is …

[HTML][HTML] Ongoing and future COVID-19 vaccine clinical trials: challenges and opportunities

R Dal-Ré, LG Bekker, C Gluud, S Holm… - The Lancet Infectious …, 2021 - thelancet.com
… of COVID-19 vaccines will seriously affect the ongoing phases 2 and 3 randomised
placebo-controlled trials assessing SARS-CoV-2 vaccine … and future trials of other COVID-19

[HTML][HTML] Looking beyond COVID-19 vaccine phase 3 trials

JH Kim, F Marks, JD Clemens - Nature medicine, 2021 - nature.com
… of COVID-19 vaccine efficacy in clinical trials by several … for the next steps to ensure vaccination
of the global population is … doses of high-quality vaccines, support for vaccine purchase, …

Clinical endpoints for evaluating efficacy in COVID-19 vaccine trials

DV Mehrotra, HE Janes, TR Fleming… - Annals of internal …, 2021 - acpjournals.org
… on study endpoints in COVID-19 vaccine efficacy trials. First, … comparison of the efficacy of
vaccine candidates, overall and … COVID-19 as well as assessment of the longer-term vaccine

[HTML][HTML] COVID-19 vaccine trials in Africa

M Makoni - The Lancet Respiratory Medicine, 2020 - thelancet.com
… -CoV2373 vaccine candidate or other COVID-19 vaccines in African … trial, also led by Madhi,
of a COVID-19 vaccine in South Africa commenced on June 23, which was the first vaccine

Understanding COVID-19 vaccine efficacy

M Lipsitch, NE Dean - Science, 2020 - science.org
… A 69-year old receives a COVID-19 vaccine in a Phase 3 trial. It is important to understand
how different groups respond to COVID-19 vaccines to establish the most effective …

A strategic approach to COVID-19 vaccine R&D

L Corey, JR Mascola, AS Fauci, FS Collins - Science, 2020 - science.org
… Although much of this focus is on trials in the United States, the COVID-19 Prevention
Networks established under the ACTIV program have a global focus, and coordination with the …

Evolution of the COVID-19 vaccine development landscape

TT Le, JP Cramer, R Chen, S Mayhew - Nat Rev Drug Discov, 2020 - nature.com
… Possible end points for consideration in COVID-19 vaccine trials include clinical disease of
… the trial population is of key importance for advanced-stage COVID-19 vaccine trials. The …