YW Zhou, Y Xie, LS Tang, D Pu, YJ Zhu… - Signal transduction and …, 2021 - nature.com
… pathogenesis of COVID-19. Both the virus and host factors are potential targets for antiviral … therapeutic strategies of COVID-19 have been classified into “targetvirus” and “target host” …
… targets for antiviral activity: spike (S) protein, the main viral protease (M Pro ), and RNA-dependent RNA polymerase (RdRp). Aspects of these targets … -CoV-2 targets. Listed are the main …
… Vaccines are urgently needed to control the coronavirus disease 2019 (COVID-19) … viral elements are used in COVID-19 vaccine candidates, why they might act as good targets …
… Viral entry is dependent on the attachment and fusion of viral membrane with plasma … this review and the ongoing COVID-19 pandemic is the role of lipid rafts in viral entry into the host …
G Li, R Hilgenfeld, R Whitley, E De Clercq - Nature Reviews Drug …, 2023 - nature.com
… COVID-19 and other infectious diseases with regard to drug repurposing strategies, pan-coronavirus drug targets, in … for these viraltargets at various stages of the viral life cycle (Fig. 2). …
A Saxena - Journal of biosciences, 2020 - Springer
… The causative virus of COVID-19 pandemic, SARS-CoV-2 virus is a part Betacoronavirus subfamily and is believed to have crossed the species barrier to infect humans due to zoonotic …
T Wang, Y Cao, H Zhang, Z Wang, CH Man… - MedComm, 2022 - Wiley Online Library
… Although the exact role of liver injury in COVID-19 development remained under discussion, 67 viral infection-induced elevation of aspartate aminotransferase (AST) and alanine …
AG Ayele, EF Enyew, ZD Kifle - Metabolism Open, 2021 - Elsevier
… Thus, this review aimed to focus on the most promising therapeutic targets being repurposed against COVID-19 and viral elements that are used in COVID-19 vaccine candidates. …
YT Wondmkun, OA Mohammed - Biologics: Targets and Therapy, 2020 - Taylor & Francis
… Accordingly, numerous drug targets are identified by scientists. Among … targets for COVID-19, and highlights antiviral strategies which depend on molecular interactions between viral …