Cytokine storm in COVID-19: immunopathogenesis and therapy

C Zanza, T Romenskaya, AC Manetti, F Franceschi… - Medicina, 2022 - mdpi.com
… inhibitors have been developed and successfully used in immune-rheumatological
pathologies, including conditions characterized by cytokine storm syndrome (CSS). Hence, as the …

[HTML][HTML] The COVID-19 cytokine storm; what we know so far

D Ragab, H Salah Eldin, M Taeimah… - Frontiers in …, 2020 - frontiersin.org
… and acute respiratory distress syndrome (ARDS) in about 15 % of the cases. Mortality in
COVID-19 patients has been linked to the presence of the so-called “cytokine storm” induced by …

The cytokine storm and COVID19

B Hu, S Huang, L Yin - Journal of medical virology, 2021 - Wiley Online Library
… An outbreak of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) has rapidly spread throughout the world. The initial …

Cytokine storm in COVID-19: pathogenesis and overview of anti-inflammatory agents used in treatment

M Soy, G Keser, P Atagündüz, F Tabak… - Clinical …, 2020 - Springer
… complicated by macrophage activation syndrome and cytokine storm. Various genetic … of
cytokine storm in COVID-19. Once, immunologic complications like cytokine storm occur, anti-…

COVID-19: Pathogenesis, cytokine storm and therapeutic potential of interferons

SH Nile, A Nile, J Qiu, L Li, X Jia, G Kai - Cytokine & growth factor reviews, 2020 - Elsevier
… are effective in Covid-19-infected patients with cytokine storm syndrome, IL-6 blockade using
… disposal to treat those patients most at risk of dying from Covid-19-induced cytokine storms. …

Preliminary predictive criteria for COVID-19 cytokine storm

R Caricchio, M Gallucci, C Dass, X Zhang… - Annals of the …, 2021 - ard.bmj.com
syndrome, haemophagocytic lymphohistiocytosis and the HScore did not identify the COVID-19
cytokine storm (… the CS occurring in patients with COVID-19. The criteria can be readily …

Is a “cytokine storm” relevant to COVID-19?

P Sinha, MA Matthay, CS Calfee - JAMA internal medicine, 2020 - jamanetwork.com
… However, on the other hand, hypercytokinenemia due to dysregulated immune response or
cytokine storm syndrome can lead to pulmonary and non-pulmonary organ damage that may …

In the eye of the COVID-19 cytokine storm

N Vaninov - Nature Reviews Immunology, 2020 - nature.com
… distress syndrome (ARDS) and robust cytokine storm are the hallmark of severe COVID-19
cases. … cell compartment, such as IL-6 inhibitors, to treat COVID-19- associated inflammation. …

COVID-19 cytokine storm: targeting the appropriate cytokine

RQ Cron - The Lancet Rheumatology, 2021 - thelancet.com
… approach to treating various cytokine storm syndromes, COVID-19 and others, should result
… criteria for cytokine storm syndrome) from cytokine-targeted treatments of COVID-19, as well …

Confronting the controversy: interleukin-6 and the COVID-19 cytokine storm syndrome

LYC Chen, RL Hoiland, S Stukas… - European …, 2020 - Eur Respiratory Soc
… and demonstrate that cytokine storm syndrome may play an important role in severe
respiratory failure and mortality caused by COVID-19. Definition of cytokine storm syndrome