Calming the cytokine storm in COVID-19

RQ Cron, R Caricchio, WW Chatham - Nature medicine, 2021 - nature.com
… Many who die from COVID-19 suffer hyper-inflammation with features of cytokine storm
syndrome (CSS) and associated acute respiratory distress syndrome 1,2 . Although the antiviral …

COVID19: Consider IL6 receptor antagonist for the therapy of cytokine storm syndrome in SARS‐CoV‐2 infected patients

C Chakraborty, AR Sharma… - Journal of medical …, 2020 - Wiley Online Library
… Tocilizumab can be used to treat cytokine storm of the COVID-19IL-6 level is significantly
increased in serum in COVID-19 infected severe patients. IL-6 is a one of the major cytokines

An inter-correlated cytokine network identified at the center of cytokine storm predicted COVID-19 prognosis

Y Liu, D Chen, J Hou, H Li, D Cao, M Guo, Y Ling… - Cytokine, 2021 - Elsevier
… distress syndrome (ARDS) in patients with COVID-19. Although multiple cytokines are …
mediators of SARS-CoV-2 induced cytokine storm and their predictive values have not been fully …

Cytokine release syndrome in COVID-19: a major mechanism of morbidity and mortality

Y Que, C Hu, K Wan, P Hu, R Wang, J Luo… - International reviews …, 2022 - Taylor & Francis
… shown to be effective in patients with cytokine storm syndromes [Citation66], and further …
alternative for the treatment of cytokine release syndrome in patients with COVID-19 [Citation67]. …

High dose subcutaneous Anakinra to treat acute respiratory distress syndrome secondary to cytokine storm syndrome among severely ill COVID-19 patients

E Iglesias-Julian, M Lopez-Veloso… - Journal of …, 2020 - Elsevier
… As in rHLH/MAS, anti-cytokine therapy has been successfully used in COVID-19 patients, …
Given the relevant role of IL-6 in COVID-19 infection, at our institution, IL-6 levels are routinely …

Infliximab against severe COVID-19-induced cytokine storm syndrome with organ failure—a cautionary case series

A Stallmach, A Kortgen, F Gonnert, SM Coldewey… - Critical care, 2020 - Springer
… , as an experimental therapy in patients with severe COVID-19 in the absence of IBD. In this
… confirmed COVID-19 in comparison with a contemporaneous group of COVID-19 receiving …

Discrimination of COVID19 from inflammation‐induced cytokine storm syndromes using disease‐related blood biomarkers

C Kessel, R Vollenberg… - Arthritis & …, 2021 - Wiley Online Library
… demonstrating a clear association of cytokine storm with severe COVID-19 are still lacking. …
COVID-19 does indeed mimic the conditions found in these classic cytokine storm syndromes

Post-COVID-19 syndrome

JD Pierce, Q Shen, SA Cintron, JB Hiebert - Nursing research, 2022 - journals.lww.com
… may result in a cytokine storm and eventually a systemic inflammatory response … cytokines
may cause a cytokine storm. A cytokine storm occurs when an overabundance of cytokines

Biosensors for managing the COVID-19 cytokine storm: challenges ahead

SM Russell, A Alba-Patino, E Baron, M Borges… - ACS …, 2020 - ACS Publications
… management must be rapid, sufficiently sensitive to detect cytokines in whole blood, and …
COVID-19 cytokine storm, including the main inflammation biomarkers linked to this syndrome. …

[HTML][HTML] Understanding the cytokine storm during COVID-19: Contribution of preexisting chronic inflammation

P Miossec - European Journal of Rheumatology, 2020 - ncbi.nlm.nih.gov
syndrome developed in a few hours (8). These examples show that the cytokine storm in
COVID-19 … This systemic cytokine storm combines the massive elevation in the blood of CRP …