… To evaluate the overall quality of the loci defined by the physical CGI Library, we calculated
two metrics, the G + C content and CpG dinucleotide frequency, and compared this to the …

… : the CpG island fraction, representing 1 to 2% of the total genome and containing all the
sites that are consistently nonmethylated at all stages of development; and the remaining 98% …

… To evaluate the accuracy of CpGcluster and compare it to other programs, we assembled
a set of test sequences on the basis of an experimental CGI library [33]. This physical library …

… As CpG islands overlap transcription units they can be used … , either by probing cDNA libraries
or by searching databases. … the CpG island for this gene along with other CpG island-like …

… That such features exist is evident from the example of CpG islands, originally defined as …
We look critically at CpG island biology in the context of the more detailed genome …

… Methylation occurs frequently at 5’-cytosine of the CpG dinucleotides in vertebrate genomes;
however, this epigenetic feature is rarely observed in CpG islands (CGIs) or CpG clusters in …

… CpG islands (CGIs) are CpG-rich regions compared to CpG-… Accurate identification of CpG
islands with epigenetic regulatory … A new approach (CpG mutual information, CpG_MI) was …

… of CpG island libraries is that all clones in the library are represented equally, in contrast to
cDNA libraries, in … Interestingly, the CpG island clones appear to contain very low numbers of …

… to be CpG island poor, whereas Chr 22 appears to be CpG island rich. We have constructed
and validated CpG island libraries … of CpG islands found on these two chromosomes. These …

… A more recent estimate, based on hybridization to a library of 375 CpG island-like sequences,
showed that 37 (or 9.9%) were derived from rDNA (S. Cross, personal communication). …