COVID-19 severity shifts the cytokine milieu toward a proinflammatory state in Egyptian patients: a cross-sectional study

ML Salem, MM Eltoukhy, RE Shalaby… - … Interferon & Cytokine …, 2023 - liebertpub.com
… distinct cytokine profiles throughout the COVID-19 severity … cytokine shift that is exacerbated
in higher COVID-19cytokine surge among severe and critically ill COVID-19 patients from …

[HTML][HTML] Identification of immune correlates of fatal outcomes in critically ill COVID-19 patients

, … Protective T cell Immunology for COVID-19  … - PLoS …, 2021 - journals.plos.org
… Our data argue against the notion that a hallmark of COVID-19 is an overwhelming “cytokine
storm”, a model that has recently been questioned [44,68,69]. Instead, a more complex and …

[HTML][HTML] Factors of severity in patients with COVID-19: cytokine/chemokine concentrations, viral load, and antibody responses

JS Kwon, JY Kim, MC Kim, SY Park… - The American journal …, 2020 - ncbi.nlm.nih.gov
cytokine/chemokine profiles during the disease course and identified the factors related to the
severity of COVID-19… -10, MIG, and IL-6 were elevated in the severe and critical group at 5–…

Elevated levels of pleiotropic interleukin-6 (IL-6) and interleukin-10 (IL-10) are critically involved with the severity and mortality of COVID-19: An updated longitudinal …

S Jafrin, MA Aziz, MS Islam - Biomarker Insights, 2022 - journals.sagepub.com
… In COVID-19 patients, IL-6 is produced in response to antigens from several immune cell …
of circulating IL-6 was critically higher among the COVID-19 patients from severe to the critical

[HTML][HTML] Serial measurement of cytokines strongly predict COVID-19 outcome

HS Ozger, R Karakus, EN Kuscu, UE Bagriacik… - PloS one, 2021 - journals.plos.org
… The effect of serum cytokine profiles on the severity of COVID-19 patients has been … of
severe and critical COVID-19 cases and the heterogeneity of the sampling time of sera for …

[HTML][HTML] Comprehensive cytokine profiling of patients with covid-19 receiving tocilizumab therapy

A Lebedeva, I Molodtsov, A Anisimova… - International journal of …, 2022 - mdpi.com
… -19. Overall, our results provide an insight into the cytokine cascade in COVID-19 patients
and suggest that IL-6 receptor … guidelines for the treatment of severe and critical COVID-19. …

[HTML][HTML] D-dimer levels and characteristics of lymphocyte subsets, cytokine profiles in peripheral blood of patients with severe COVID-19: A systematic review and …

H Zhang, H Wu, D Pan, W Shen - Frontiers in Medicine, 2022 - frontiersin.org
… is essential for critically COVID-19 patients. we aimed to investigate the correlation among
D-dimer levels, lymphocyte subsets, cytokines, and disease severity in COVID-19 patients. …

[HTML][HTML] Immunotherapy of COVID-19: inside and beyond IL-6 signalling

G Zizzo, A Tamburello, L Castelnovo, A Laria… - Frontiers in …, 2022 - frontiersin.org
… suggests that in critical COVID-19, strong elevation of IL-6 (eg… roles of IL-6 in the inflammatory
cascade of COVID-19 according to … of IL-6 inhibitors (IL-6i). Created with Biorender.com. …

[HTML][HTML] Inflammatory mediators profile in patients hospitalized with COVID-19: A comparative study

A Tufa, TH Gebremariam, T Manyazewal… - Frontiers in …, 2022 - frontiersin.org
… the proinflammatory cytokines IL-6 and IL-8 in COVID-19 patients with severe sickness (39).
IL-10 is a … As a result, the critical biomarkers determined in this study may aid in clinical care …

[HTML][HTML] Severe immunosuppression and not a cytokine storm characterizes COVID-19 infections

KE Remy, M Mazer, DA Striker, AH Ellebedy… - JCI insight, 2020 - ncbi.nlm.nih.gov
… was to determine whether critically ill COVID-19 patients have an … cytokines in COVID-19,
septic, and CINS patients and healthy control participants (Table 2). Patients with COVID-19