Critical determinants of cytokine storm and type I interferon response in COVID-19 pathogenesis

S Ramasamy, S Subbian - Clinical microbiology reviews, 2021 - Am Soc Microbiol
… Therefore, therapeutic approaches involving anti-cytokine/anti-cytokine-signaling and IFN …
review describes critical host and viral factors underpinning the inflammatory “cytokine storm” …

[HTML][HTML] Cytokine storm: the primary determinant for the pathophysiological evolution of COVID-19 deterioration

R Chen, Z Lan, J Ye, L Pang, Y Liu, W Wu… - Frontiers in …, 2021 - frontiersin.org
… patients with severe and critical cases of COVID-19. The determinants of the severity of
COVID-19 disease deterioration are closely related mainly to the cytokine storm and a decrease …

Erratum for Ramasamy and Subbian,“critical determinants of cytokine storm and type I interferon response in COVID-19 pathogenesis”

S Ramasamy, S Subbian - Clinical microbiology reviews, 2021 - Am Soc Microbiol
… cellular pathways and networks for cytokine induction and IFN antagonism during COVID-19”
should read “Interaction of cellular pathways and networks for cytokine induction and IFN …

[HTML][HTML] Cytokine storm—definition, causes, and implications

D Jarczak, A Nierhaus - International journal of molecular sciences, 2022 - mdpi.com
… systems consist of effector cells producing cytokines (interleukins, interferons, chemokines,
… chain reactions resulting in a massive release of cytokines. This may result in a drastic self-…

The cytokine storm in COVID-19: Further advances in our understanding the role of specific chemokines involved

F Coperchini, L Chiovato, G Ricci, L Croce… - Cytokine & Growth …, 2021 - Elsevier
cytokine/chemokine network is crucial in the onset and maintenance of the “cytokine storm”,
… a specific focus on their role in the cytokine storm and ultimately with their ability to predict …

[HTML][HTML] Biomarkers of cytokine storm as red flags for severe and fatal COVID-19 cases: A living systematic review and meta-analysis

AKG Melo, KM Milby, ALMA Caparroz, ACPN Pinto… - PloS one, 2021 - journals.plos.org
… To describe the laboratory parameters and biomarkers of the cytokine storm syndrome … and
D-dimer as important biomarkers of cytokine storm syndrome. Elevated levels of interleukin-6 …

The cytokine storm and COVID‐19

B Hu, S Huang, L Yin - Journal of medical virology, 2021 - Wiley Online Library
… Excessive local release of cytokines is considered to be the determinant of pathological …
The cytokine storm leads to deleterious clinical manifestations or even acute mortality in critically

Into the eye of the cytokine storm

JR Tisoncik, MJ Korth, CP Simmons… - Microbiology and …, 2012 - Am Soc Microbiol
… infection does not seem to be a determinant of the severity of local and systemic cytokine
and that this contributes to vasodilation during this critical phase of the illness, although not all …

[HTML][HTML] Scoring cytokine storm by the levels of MCP-3 and IL-8 accurately distinguished COVID-19 patients with high mortality

L Chen, G Wang, J Tan, Y Cao, X Long, H Luo… - Signal transduction and …, 2020 - nature.com
cytokine storm and pathological phenotypes. In conclusion, this study identified chemokines
and IL-6 as determinant cytokines in severe cytokine storm. … severity of cytokine storm in the …

[HTML][HTML] Innate immunity, cytokine storm, and inflammatory cell death in COVID-19

R Karki, TD Kanneganti - Journal of Translational Medicine, 2022 - Springer
… In these cases, the combination of cytokines, particularly tumor necrosis factor (… in cytokine
storm [5, 12]. Overall, while early innate immune-mediated inflammatory responses are critical